Estabilidad acelerada del ungüento QL

ql ointment is a rectal ointment under development stage devoted to the treatment of rectal affections. the combination for the first time of quitine and lydocaine chloride in a semisolid product of oleaginous base requires the study of the stability behaviour. to obtain information on its stability, a study was carried out under the established conditions. 3 pilot batches ql01, ql02 and ql03, stored at a temperature of 40 2 c, were analyzed. the studies were conducted at 0, 1, 2, 3 and 6 months. no changes were observed neither in the organoleptic properties, nor in the sedimentation stability and the extensibility area. the pseudoplastic thixotropic flow characteristic of this type of system was maintained after 6 months. the active principles were stable under the assayed conditions