%0 Journal Article
%T Estabilidad acelerada del ung¨¹ento QL
%A Su¨¢rez P¨¦rez
%A Yania
%A Garc¨ªa Pulpeiro
%A Oscar
%A Cueto Le¨®n
%A Marisel
%J Revista Cubana de Farmacia
%D 2008
%I ECIMED
%X ql ointment is a rectal ointment under development stage devoted to the treatment of rectal affections. the combination for the first time of quitine and lydocaine chloride in a semisolid product of oleaginous base requires the study of the stability behaviour. to obtain information on its stability, a study was carried out under the established conditions. 3 pilot batches ql01, ql02 and ql03, stored at a temperature of 40 2 c, were analyzed. the studies were conducted at 0, 1, 2, 3 and 6 months. no changes were observed neither in the organoleptic properties, nor in the sedimentation stability and the extensibility area. the pseudoplastic thixotropic flow characteristic of this type of system was maintained after 6 months. the active principles were stable under the assayed conditions
%K rectal ointment
%K stability
%K quitine
%K lydocaine chloride.
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0034-75152008000100010&lng=en&nrm=iso&tlng=en