Dise？o de una formulación antimicótica

a formulation with miconazole nitrate 2 % is developed in an appropiate hydrosoluble cream, which meets all the physical, chemical, microbiologic and biologic requirements for this type of pharmaceutical form. it was proved that the product should be put into amber glass flasks or into lacquered aluminum tubes. besides having an adecuate physical stability during three years. the content of the active principle was kept within the established limits up to the 16 months. the antifungal activity of the preparation as well as its therapeutic effectiveness were also demonstrated.