%0 Journal Article
%T Diseˋo de una formulaci車n antimic車tica
%A G車mez Carril
%A Martha
%A L車pez Guerra
%A Martha
%A Garc赤a Sim車n
%A Gast車n
%J Revista Cubana de Farmacia
%D 1998
%I ECIMED
%X a formulation with miconazole nitrate 2 % is developed in an appropiate hydrosoluble cream, which meets all the physical, chemical, microbiologic and biologic requirements for this type of pharmaceutical form. it was proved that the product should be put into amber glass flasks or into lacquered aluminum tubes. besides having an adecuate physical stability during three years. the content of the active principle was kept within the established limits up to the 16 months. the antifungal activity of the preparation as well as its therapeutic effectiveness were also demonstrated.
%K chemistry
%K pharmaceutical [methods]
%K antifungal agents [chemistry]
%K miconazole [chemistry]
%K ointments [chemistry]
%K drug design
%K drug stability
%K clinical trials
%K phase i
%K clinical trials
%K phase ii..
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0034-75151998000100002&lng=en&nrm=iso&tlng=en