Desarrollo y validación de un método de determinación por espectrofotometría visible de antimoniato de meglumina en inyectables

in this paper we present the results obtained during the development and validation of an analytical methodology by a colorimetric method for the assay of meglumine antimoniate in injections. the quantification implies the formation of a colored complex resulting after of meglumine antimoniate and potassium iodure in acid media. the absorbance was made at 352 nm. the validated methodology may be used as a part of quality control with release purpose and also, in chemical stability studies of the injections. as validation parameters, we studied selectivity, lineality, precision, accuracy and robustness.