%0 Journal Article
%T Desarrollo y validaci¨®n de un m¨¦todo de determinaci¨®n por espectrofotometr¨ªa visible de antimoniato de meglumina en inyectables
%A Rojas
%A Jaime H
%A Sierra
%A Noralba
%A Arboleda
%A Eduardo
%A Bello
%A Mario
%J Revista Colombiana de Ciencias Qu¨ªmico - Farmac¨¦uticas
%D 2007
%I Scientific Electronic Library Online
%X in this paper we present the results obtained during the development and validation of an analytical methodology by a colorimetric method for the assay of meglumine antimoniate in injections. the quantification implies the formation of a colored complex resulting after of meglumine antimoniate and potassium iodure in acid media. the absorbance was made at 352 nm. the validated methodology may be used as a part of quality control with release purpose and also, in chemical stability studies of the injections. as validation parameters, we studied selectivity, lineality, precision, accuracy and robustness.
%K meglumine antimomiate
%K colorimetric assay
%K validation.
%U http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0034-74182007000200004&lng=en&nrm=iso&tlng=en