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May 13, 2021Open    AccessArticle

Hemophagocytic Lymphohistiocytosis Secondary to Varicella Zoster with Acute Liver Failure

Satesh Ramasundram, Chong Kah Kian
Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life threatening syndrome of excessive immune activation. This condition can be inherited or secondary to other diseases. The therapeutic success is directly related to the rapid diagnosis with the patient who have high clinical suspicious index such as febrile illness with cytopenia, liver enzyme derangement, raised serum ferritin and low fibrinogen levels. Infection is a common trigger both in those with a genetic predisposition and...
Open Access Library J. Vol.8, 2021
Doi:10.4236/oalib.1107367


Dec 31, 2020Open    AccessArticle

Experience of Treating 69 Cases of Gastroc Ardical Syndrome with Traditional Chinese Medicine

Yanzhi Wang, Binglin Liu, Zhenchao Liu, Guang Liu, Donghao Zhou
Aims: To explore the clinical efficacy of TCM in the treatment of gastroc ardical syndrome, and to summarize the experience of TCM treatment of gastroc ardical syndrome. Method: A retrospective summary of 69 patients with gastroc ardical syndrome treated by Binglin Liu, an old expert in Linyi Hospital of Traditional Chinese Medicine, according to the patient’s clinical symptoms and prescriptions, summarizes the TCM classification and treatment methods of this disease. Results: The TCM syndromes ...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1107001


Nov 11, 2020Open    AccessArticle

The Association between Pathologies of Voice and Gastro-Oesophageal Reflux Disease (GORD)

Rasan Burhan, Jalal Moradzadeh, Ethan Smallwood, Thomas Kiwanuka, Samuel Ajayi
Voice and speaking are integral parts of a person’s self-identity and ability to communicate on a day-to-day basis. There have been numerous studies investigating the link between gastro-esophageal reflux disease and its concomitant association with a range of other disorders across the breadth of medicine. In this review, we will focus on the relationship between conditions which contribute to pathologies of voice and GORD. These will include Laryngopharyngeal reflux, Globus Pharyngeus and Paro...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106890


Aug 18, 2020Open    AccessArticle

Metabolic Alkalosis Associated Fluid and Electrolyte Disorders Revealing an Upper Digestive Tract Condition

Ameth Dieng, M. A. Ba, A. T. Lemrabott, M. Diop, A. Sy, M. Ndongo, B. Ndiaye, M. S. Diawara, M. Faye, Mo Faye, B. Ba, N. Keita, S. Diagne, M. M. Cissé
We report a case of a 66-year-old female patient with ischemic cardiomyopathy, who was referred in Nephrology Department for the management of a renal impairment associated-severe hyponatremia, hypokalemia and hypochloremia that occurred after vomiting episodes evolving since 1 month. On admission, the patient was calm with a psychomotor retardation occurring in a context of moderate dehydration. Arterial blood gas analysis outlined a severe metabolic alkalosis. An extra-renal cause of these met...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106338


Apr 24, 2020Open    AccessArticle

Reversing Back to the Basic: Infection Control Strategies

Mohammad Miah, Syeda Nafisa, Tara Bartley, Sandeep Kaur, Ahmed Ashoub
Healthcare-associated infections are estimated to cost the NHS approximately £1 billion a year. In addition to increased costs, each one of these infections means additional use of NHS resources, greater patient discomfort and a decrease in patient safety. In the wake of the growing burden of healthcare- associated infections (HCAIs), the increasing severity of illness and complexity of treatment, superimposed by multi-drug resistant (MDR) pathogen infections, healthcare practitioners (HCPs) are...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106197


Apr 24, 2020Open    AccessArticle

Preoperative Management of Antiplatelet Agents for CABG Surgery Patients: A Prospective Cohort Study Focused on P2Y12 Inhibitors

Mohammad Miah, Syeda Nafisa, Liam Phelan, Sandeep Kaur, Mostafa Mehann, Ahmed Ashoub
Dual antiplatelet therapy (DAPT) using aspirin and ticlopidine, a thienopyridine P2Y12 inhibitor, was introduced, decreasing the rate of stent thrombosis to about 1%. Continuation of dual antiplatelet therapy (DAPT) until Coronary artery bypass graft (CABG) increases the risk of excessive perioperative bleeding, transfusions, and re-exploration for bleeding as shown in RCTs observational studies and metanalyses. Therefore, it is recommended that the P2Y12 inhibitor should be discontinued wheneve...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106196


Mar 20, 2020Open    AccessArticle

Referring Patients with Iron Deficiency Anaemia to Colorectal Surgery under the Two-Week Wait Rule

Mohammad Miah, Humayra Begum, Fraser Currie, Thomas Wild, Mohamad Al Saramigy
Asymptomatic colonic and gastric carcinoma may present with IDA (Iron deficiency anaemia), and seeking these conditions is a priority in patients with IDA. One of the criteria under the Two-Week Referral (TWR) rule for suspected GI malignancy is iron deficiency anaemia (IDA). Although IDA is a good marker for gastrointestinal cancer, sometimes 2WW referral guidelines are not being followed appropriately for IDA. This not only has considerable workload and financial implications but also invasive...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106169


Oct 14, 2019Open    AccessArticle

New Case of Anti-Synthetase Syndrome Associated with Cirrhosis Post HVB

Hind Omari, Ahmed Bellabah, Mohammed Tahiri, Fouad Haddad, Wafaa Hliwa, Wafaa Badre
The anti-synthetase syndrome is represented by the association of in-flammatory myopathy (polymyositis/dermatomyositis), interstitial pneu-monitis, Raynaud’s syndrome, inflammatory polyarthritis, and characteristic skin abnormalities. We found also a clinical aspects of Mechanic’s hand with high level of anti-synthetases. We report the case of a 66-year-old patient with polyar- thralgias of large and small inflammatory joints, myo
...
Open Access Library J. Vol.6, 2019
Doi:10.4236/oalib.1105753


Jul 18, 2019Open    AccessArticle

Management of Traumatic Bile Leakage

Naoki Hashimoto
Major bile leak after blunt liver trauma (BLT) is rare but challenging. Data on endoscopic management of traumatic bile leaks are scare. We conducted a ret-rospective review to evaluate the role of Endoscopic retrograde cholangi-ography (ERCP) in the management of bile leaks following blunt abdominal trauma. In addition to a high grade injury, centrally-located liver injuries and initial TAE are also a significant risk factor for
...
Open Access Library J. Vol.6, 2019
Doi:10.4236/oalib.1105556


Jun 28, 2019Open    AccessArticle

Response of HCV Yemeni Patients to Sofosbuvir/Ledipasvir in Combination with Ribavirin

Abdulgafoor Kassim, Ramea Alathwary, Talal Al-hogami
Objectives: To study the effectiveness and safety of ledipasvir-sofosbuvir plus ribavirin treatment in Yemeni patient with HCV infection. Design: Prospective study of sixty-five Yemeni patients confirmed with HCV infection during the period from January 2017 to April 2018. Setting: Gastrointestinal and liver diseases specialized center in Ibb city, Yemen. Subjects: Patients with proved HCV infection by PCR. Results: We collected 6
...
Open Access Library J. Vol.6, 2019
Doi:10.4236/oalib.1105507


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