OALib Journal
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Mar 17, 2021Open    AccessArticle

Exceptional Localization of a Prolactinoma as Part of Familial Isolated Pituitary Adenomas

Hind Asbar, Maryame Benlafqih, Sara Askaoui, Sana Rafi, Ghizlane El Mghari, Nawal El Ansari
The syndrome of familial isolated pituitary adenomas (FIPA) or predisposition to pituitary adenomas (PAP) is characterized by the presence within the same family of at least two isolated pituitary adenomas without any other type of associated endocrine tumor. These pituitary tumors may present as homogenous with the same tumor phenotype or heterogeneous with different patterns of pituitary tumor phenotypes (GH, Prolactine, ACTH secretion or non-functioning pituitary adenomas) within the same kin...
Open Access Library J. Vol.8, 2021
Doi:10.4236/oalib.1107229


Aug 18, 2020Open    AccessArticle

Metabolic Alkalosis Associated Fluid and Electrolyte Disorders Revealing an Upper Digestive Tract Condition

Ameth Dieng, M. A. Ba, A. T. Lemrabott, M. Diop, A. Sy, M. Ndongo, B. Ndiaye, M. S. Diawara, M. Faye, Mo Faye, B. Ba, N. Keita, S. Diagne, M. M. Cissé
We report a case of a 66-year-old female patient with ischemic cardiomyopathy, who was referred in Nephrology Department for the management of a renal impairment associated-severe hyponatremia, hypokalemia and hypochloremia that occurred after vomiting episodes evolving since 1 month. On admission, the patient was calm with a psychomotor retardation occurring in a context of moderate dehydration. Arterial blood gas analysis outlined a severe metabolic alkalosis. An extra-renal cause of these met...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106338


Mar 17, 2020Open    AccessArticle

Assessment of Serum Electrolyte Levels & HbA1C Levels among Type 2 Diabetic Sudanese Patients with Macrovascular Complications in Khartoum State

Ragda Hafaz Ramadan, Abdulmwla Muhammed Abdullah
Background: Recently epidemiological studies have shown that type 2 diabetes mellitus is great a risk factor for cardiovascular mortality. Electrolyte abnormalities are commonly encountered in chronic diabetes mellitus type 2 patients. Aim: The aim of this study was to estimate serum electrolyte levels & HbA1C levels among Sudanese diabetic Patients with macrovascular complications in Khartoum State, Sudan. Materials & Methods: In this case, control hospital based study conducted in Khartoum sta...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106110


Jan 14, 2020Open    AccessArticle

Bilateral Drop-Foot Due to Diabetes Mellitus Disease

Zeliha Unlu, Merve Ciniviz
Diabetes mellitus (DM) is a disease in which broad spectrum neuropathies including x asymptomatic distal sensory neuropathies as well as severe radiculo- pexopathies are observed [1]. Diabetic neuropathy; symmetrical distal polyneuropathies, focal and multifocal neuropathies, inflammatory demyelinating neuropathies may occur in various forms [2]. Herein, we aimed to present a case of clinical and electroneuromyographic (ENMG) stud
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Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106013


Dec 24, 2019Open    AccessArticle

The Effect of Chitooligosaccharides on Gut Microbiota in Diabetic Mice

Xin Wang, Qin Hu, Chao Dong
Chitooligosaccharides (COS) has an effect to reduce blood glucose and blood lipids and is used in adjuvant therapy for diabetes mellitus (DM), which is closely associated with gut microbiota. Therefore, it is worthy investigating whether COS exerts its effect via the gut microbiota. In this paper, we studied the response of gut microbiota in diabetic mice to COS, using the high-throughput sequencing technolo
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Open Access Library J. Vol.6, 2019
Doi:10.4236/oalib.1105961


Feb 28, 2019Open    AccessArticle

Difficulties and Countermeasures in Performance Management of Primary Health Care Institutions in China

Meng Zhou, Liqi Tian
At present, the main dilemma faced by performance management of primary health care institutions is that the total performance salary is not high, the incentives caused by the imbalance of performance wage structure, the lack of perfect performance appraisal distribution system, and the performance management level of the dean of grassroots health institutions need to be improved. Performance managem
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Open Access Library J. Vol.6, 2019
Doi:10.4236/oalib.1105068


Jul 13, 2018Open    AccessArticle

The Association between Visceral Fat, Dietary Patterns, and Comorbidities

Louay Labban, Zeina Malek
Visceral fat is technically the excess accumulation of intra-abdominal adipose tissue. This type of fat is stored further underneath the skin than subcutaneous fat and it’s actually wrapped around major organs, including liver, pancreas and kidneys. Studies have shown that visceral fat plays a distinctive and potentially dangerous role affecting hormones function and it is also associated with
...
Open Access Library J. Vol.5, 2018
Doi:10.4236/oalib.1104654


May 23, 2018Open    AccessArticle

Metabolic and IL-6-Induced Inflammatory Responses in High-Intensity Intermittent Exercise among Type 2 Diabetes Patients with Sarcopenia

Zhenchao Liu
Objective: The aim of this study was to examine the effects of high-intensity intermittent exercise (HIIE) on features of immunometabolism by comparing elderly female sarcopenia and non-sarcopenia in elderly female patients with type 2 diabetes (T2MD). Differences in metabolism and inflammatory responses between the two groups were compared. Methods: 6 elderly female sarcopenia patients with T2MD serve
...
Open Access Library J. Vol.5, 2018
Doi:10.4236/oalib.1104622


Jan 05, 2018Open    AccessArticle

Endothelial Nitric Oxide Synthase (eNOS) Glu298Asp Gene Polymorphism (G894T) as a Risk Factor for Type 2 Diabetes Mellitus in the Tunisian Population

Rihab Sendesni, Nedra Grira, Oussama Lamine, Sana Aboulkassem, Manel Ayoub, Nejla Stambouli, Ouertani Haroun, Chakib Mazigh, Zied Aouni
Introduction: Diabetes mellitus is a chronic disease whose global expansion gives it the characteristics of a pandemic. Diabetes risk factors are well known. In this work we proposed to study the role of genetic polymorphism of the eNOS G894T gene in the development of diabetes on the one hand and of these degenerative complications other. Methods: We conducted a prospective case-control study in which we inclu
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Open Access Library J. Vol.5, 2018
Doi:10.4236/oalib.1104171


Dec 05, 2017Open    AccessArticle

Tetra Primer ARMS PCR Optimization to Detect Single Nucleotide Polymorphism of the KLF14 Gene

Ana Sofia Zabala, Miriam Ester Vasquez Gomez, Micaela Fernanda Alvarez, Susana Siewert
GWAS (genome-wide association studies) have associated Type 2 Diabetes Mellitus with the single nucleotide polymorphism (SNPs) rs972283 (A/G) of KLF14 gene with in a global population. The most common techniques used to analyze SNPs are time consuming, multi-step process and require expensive instruments. Therefore, in order to overcome these problems, we have developed a new, rapid and cost effective T-ARMS PCR assay to genotype
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Open Access Library J. Vol.4, 2017
Doi:10.4236/oalib.1104145


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