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PLOS ONE

ISSN Print: 1932-6203

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Oral Delivery of Double-Stranded RNAs and siRNAs Induces RNAi Effects in the Potato/Tomato Psyllid, Bactericerca cockerelli

Hada Wuriyanghan,Cristina Rosa,Bryce W. Falk

Age-Related Memory Impairment Is Associated with Disrupted Multivariate Epigenetic Coordination in the Hippocampus

James F. Castellano, Bonnie R. Fletcher, Bennett Kelley-Bell, David H. Kim, Michela Gallagher, Peter R. Rapp

Regulation of Synaptic Vesicle Docking by Different Classes of Macromolecules in Active Zone Material

Joseph A. Szule, Mark L. Harlow, Jae Hoon Jung, Francisco F. De-Miguel, Robert M. Marshall, Uel J. McMahan

A Coupled Discrete/Continuum Model for Describing Cancer-Therapeutic Transport in the Lung

Karin Erbertseder, Johannes Reichold, Bernd Flemisch, Patrick Jenny, Rainer Helmig

Formulation of a mmaA4 Gene Deletion Mutant of Mycobacterium bovis BCG in Cationic Liposomes Significantly Enhances Protection against Tuberculosis

Steven C. Derrick, Dee Dao, Amy Yang, Kris Kolibab, William R. Jacobs, Sheldon L. Morris

Transient Expression of Hemagglutinin Antigen from Low Pathogenic Avian Influenza A (H7N7) in Nicotiana benthamiana

Selvaraju Kanagarajan, Conny Tolf, Anneli Lundgren, Jonas Waldenstr？m, Peter E. Brodelius

HPV16 Oncoproteins Induce MMPs/RECK-TIMP-2 Imbalance in Primary Keratinocytes: Possible Implications in Cervical Carcinogenesis

Laura Beatriz da Silva Cardeal, Enrique Boccardo, Lara Termini, Tatiana Rabachini, Maria Antonieta Andreoli, Celso di Loreto, Adhemar Longatto Filho, Luisa Lina Villa, Silvya Stuchi Maria-Engler

Mechanisms of Adaptation from a Multiple to a Single Step Recovery Strategy following Repeated Exposure to Forward Loss of Balance in Older Adults

Christopher P. Carty, Neil J. Cronin, Glen A. Lichtwark, Peter M. Mills, Rod S. Barrett

Characterization of OxyR as a Negative Transcriptional Regulator That Represses Catalase Production in Corynebacterium diphtheriae

Ju-Sim Kim, Randall K. Holmes

Generation of a Convalescent Model of Virulent Francisella tularensis Infection for Assessment of Host Requirements for Survival of Tularemia

Deborah D. Crane,Dana P. Scott,Catharine M. Bosio

Dopamine D1–D2 Receptor Heteromer in Dual Phenotype GABA/Glutamate-Coexpressing Striatal Medium Spiny Neurons: Regulation of BDNF, GAD67 and VGLUT1/2

Melissa L. Perreault,Theresa Fan,Mohammed Alijaniaram,Brian F. O'Dowd,Susan R. George

Deficiency of the LIM-Only Protein FHL2 Reduces Intestinal Tumorigenesis in Apc Mutant Mice

Charlotte Labalette,Yann Nou？t,Florence Levillayer,Sabine Colnot,Ju Chen,Valere Claude,Michel Huerre,Christine Perret,Marie-Annick Buendia,Yu Wei

Pilot Study of the Association of the DDAH2 ？449G Polymorphism with Asymmetric Dimethylarginine and Hemodynamic Shock in Pediatric Sepsis

Scott L. Weiss,Min Yu,Lawrence Jennings,Shannon Haymond,Gang Zhang,Mark S. Wainwright

c-FLIP Degradation Mediates Sensitization of Pancreatic Cancer Cells to TRAIL-Induced Apoptosis by the Histone Deacetylase Inhibitor LBH589

John Kauh,Songqing Fan,Mingjing Xia,Ping Yue,Lily Yang,Fadlo R. Khuri,Shi-Yong Sun

Metastasis-Inducing S100A4 and RANTES Cooperate in Promoting Tumor Progression in Mice

Birgitte Forst,Matilde Thye Hansen,J？rg Klingelh？fer,Henrik Devitt M？ller,Gitte Helle Nielsen,Birgitte Grum-Schwensen,Noona Ambartsumian,Eugene Lukanidin,Mariam Grigorian

A Novel Role for Wnt/Ca2+ Signaling in Actin Cytoskeleton Remodeling and Cell Motility in Prostate Cancer

Qin Wang,Andrew J. Symes,Corrina A. Kane,Alex Freeman,Joseph Nariculam,Philippa Munson,Christopher Thrasivoulou,John R. W. Masters,Aamir Ahmed

Involving Motor Capabilities in the Formation of Sensory Space Representations

Daniel Weiller,Robert M？rtin,Sven D？hne,Andreas K. Engel,Peter K？nig

A Glucose BioFuel Cell Implanted in Rats

Philippe Cinquin,Chantal Gondran,Fabien Giroud,Simon Mazabrard,Aymeric Pellissier,Fran？ois Boucher,Jean-Pierre Alcaraz,Karine Gorgy,Fran？ois Lenouvel,Stéphane Mathé,Paolo Porcu,Serge Cosnier

Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c Proteins Participate in the Suppression of Macrophage Apoptosis

Lia Danelishvili,Yoshitaka Yamazaki,Jeannie Selker,Luiz E. Bermudez

Transposable Elements Are a Major Cause of Somatic Polymorphism in Vitis vinifera L.

Grégory Carrier, Lo？c Le Cunff, Alexis Dereeper, Delphine Legrand, Fran？ois Sabot, Olivier Bouchez, Laurent Audeguin, Jean-Michel Boursiquot, Patrice This

Population Based Model of Human Embryonic Stem Cell (hESC) Differentiation during Endoderm Induction

Keith Task, Maria Jaramillo, Ipsita Banerjee

Dissecting the Clinical Heterogeneity of Autism Spectrum Disorders through Defined Genotypes

Hilgo Bruining,Leo de Sonneville,Hanna Swaab,Maretha de Jonge,Martien Kas,Herman van Engeland,Jacob Vorstman

Improving Hox Protein Classification across the Major Model Organisms

Stefanie D. Hueber,Georg F. Weiller,Michael A. Djordjevic,Tancred Frickey

α-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population

Walter E. Gall,Kirk Beebe,Kay A. Lawton,Klaus-Peter Adam,Matthew W. Mitchell,Pamela J. Nakhle,John A. Ryals,Michael V. Milburn,Monica Nannipieri,Stefania Camastra,Andrea Natali,Ele Ferrannini

Multiple Phosphatidylinositol 3-Kinases Regulate Vaccinia Virus Morphogenesis

Shannon McNulty,William Bornmann,Jill Schriewer,Chas Werner,Scott K. Smith,Victoria A. Olson,Inger K. Damon,R. Mark Buller,John Heuser,Daniel Kalman

Induction of Heme Oxygenase-1, Biliverdin Reductase and H-Ferritin in Lung Macrophage in Smokers with Primary Spontaneous Pneumothorax: Role of HIF-1α

Delphine Goven,Anne Boutten,Véronique Le？on-Malas,Jo？lle Marchal-Sommé,Paul Soler,Jorge Boczkowski,Marcel Bonay

MicroRNA-29b Regulates the Expression Level of Human Progranulin, a Secreted Glycoprotein Implicated in Frontotemporal Dementia

Jian Jiao,Lauren D. Herl,Robert V. Farese Jr,Fen-Biao Gao

Ancient Nursery Area for the Extinct Giant Shark Megalodon from the Miocene of Panama

Catalina Pimiento,Dana J. Ehret,Bruce J. MacFadden,Gordon Hubbell

Identification of MicroRNA-21 as a Biomarker for Chemoresistance and Clinical Outcome Following Adjuvant Therapy in Resectable Pancreatic Cancer

Jin-Hyeok Hwang,Johannes Voortman,Elisa Giovannetti,Seth M. Steinberg,Leticia G. Leon,Yong-Tae Kim,Niccola Funel,Joo Kyung Park,Min A. Kim,Gyeong Hoon Kang,Sun-Whe Kim,Marco Del Chiaro,Godefridus J. Peters,Giuseppe Giaccone

Molecular, Biochemical and Genetic Characteristics of BSE in Canada

Sandor Dudas,Jianmin Yang,Catherine Graham,Markus Czub,Tim A. McAllister,Michael B. Coulthart,Stefanie Czub

Bistability and Bacterial Infections

Roy Malka,Eliezer Shochat,Vered Rom-Kedar

3-D Modelling of Megaloolithid Clutches: Insights about Nest Construction and Dinosaur Behaviour

Bernat Vila,Frankie D. Jackson,Josep Fortuny,Albert G. Sellés,àngel Galobart

ETS Transcription Factors Control Transcription of EZH2 and Epigenetic Silencing of the Tumor Suppressor Gene Nkx3.1 in Prostate Cancer

Paolo Kunderfranco,Maurizia Mello-Grand,Romina Cangemi,Stefania Pellini,Afua Mensah,Veronica Albertini,Anastasia Malek,Giovanna Chiorino,Carlo V. Catapano,Giuseppina M. Carbone

A Novel, Low-Volume Method for Organ Culture of Embryonic Kidneys That Allows Development of Cortico-Medullary Anatomical Organization

David D. R. Sebinger,Mathieu Unbekandt,Veronika V. Ganeva,Andreas Ofenbauer,Carsten Werner,Jamie A. Davies

Transcriptome Analysis of the Hippocampal CA1 Pyramidal Cell Region after Kainic Acid-Induced Status Epilepticus in Juvenile Rats

Hanna B. Laurén,Francisco R. Lopez-Picon,Annika M. Brandt,Clarissa J. Rios-Rojas,Irma E. Holopainen

Rhodococcus Bacteremia in Cancer Patients Is Mostly Catheter Related and Associated with Biofilm Formation

Fadi Al Akhrass, Iba Al Wohoush, Anne-Marie Chaftari, Ruth Reitzel, Ying Jiang, Mahmoud Ghannoum, Jeffrey Tarrand, Ray Hachem, Issam Raad

Cellular Phenotype-Dependent and -Independent Effects of Vitamin C on the Renewal and Gene Expression of Mouse Embryonic Fibroblasts

Shiu-Ming Kuo, Lana R. Burl, Zihua Hu

Genome-Wide Haplotype Changes Produced by Artificial Selection during Modern Rice Breeding in Japan

Jun-ichi Yonemaru, Toshio Yamamoto, Kaworu Ebana, Eiji Yamamoto, Hideki Nagasaki, Taeko Shibaya, Masahiro Yano

Inhibition of Melanogenesis by the Pyridinyl Imidazole Class of Compounds: Possible Involvement of the Wnt/β-Catenin Signaling Pathway

Barbara Bellei, Angela Pitisci, Enzo Izzo, Mauro Picardo

In Vivo Manganese Exposure Modulates Erk, Akt and Darpp-32 in the Striatum of Developing Rats, and Impairs Their Motor Function

Fabiano M. Cordova, Aderbal S. Aguiar, Tanara V. Peres, Mark W. Lopes, Filipe M. Gon？alves, Aline P. Remor, Samantha C. Lopes, Célso Pilati, Alexandra S. Latini, Rui D. S. Prediger, Keith M. Erikson, Michael Aschner, Rodrigo B. Leal

The Drosophila Gene RanBPM Functions in the Mushroom Body to Regulate Larval Behavior

Nadia Scantlebury,Xiao Li Zhao,Verónica G. Rodriguez Moncalvo,Alison Camiletti,Stacy Zahanova,Aidan Dineen,Ji-Hou Xin,Ana Regina Campos

Cartography of Methicillin-Resistant S. aureus Transcripts: Detection, Orientation and Temporal Expression during Growth Phase and Stress Conditions

Marie Beaume,David Hernandez,Laurent Farinelli,Cécile Deluen,Patrick Linder,Christine Gaspin,Pascale Romby,Jacques Schrenzel,Patrice Francois

What Leads Indians to Participate in Clinical Trials? A Meta-Analysis of Qualitative Studies

Jatin Y. Shah,Amruta Phadtare,Dimple Rajgor,Meenakshi Vaghasia,Shreyasee Pradhan,Hilary Zelko,Ricardo Pietrobon

Aldehyde Dehydrogenase (ALDH) Activity Does Not Select for Cells with Enhanced Aggressive Properties in Malignant Melanoma

Lina Prasmickaite,Birgit ？. Enges？ter,Nirma Skrbo,Tina Hellenes,Alexandr Kristian,Nina K. Oliver,Zhenhe Suo,Gunhild M. M？landsmo

DNA Double-Strand Breaks Induced by Cavitational Mechanical Effects of Ultrasound in Cancer Cell Lines

Yukihiro Furusawa, Yoshisada Fujiwara, Paul Campbell, Qing-Li Zhao, Ryohei Ogawa, Mariame Ali Hassan, Yoshiaki Tabuchi, Ichiro Takasaki, Akihisa Takahashi, Takashi Kondo

Rapid Accumulation of Polymorphonuclear Neutrophils in the Corpus luteum during Prostaglandin F2α-Induced Luteolysis in the Cow

Koumei Shirasuna, Sineenard Jiemtaweeboon, Sybille Raddatz, Akane Nitta, Hans-Joachim Schuberth, Heinrich Bollwein, Takashi Shimizu, Akio Miyamoto

Deep Evolutionary Conservation of an Intramolecular Protein Kinase Activation Mechanism

Jingfen Han, Diego Miranda-Saavedra, Nathan Luebbering, Aman Singh, Gary Sibbet, Michael A. J. Ferguson, Vaughn Cleghon

Keratinocyte-Targeted Overexpression of the Glucocorticoid Receptor Delays Cutaneous Wound Healing

Ana Sanchis, Lorena Alba, Víctor Latorre, Lisa M. Sevilla, Paloma Pérez

Malignant B Cells Induce the Conversion of CD4+CD25？ T Cells to Regulatory T Cells in B-Cell Non-Hodgkin Lymphoma

Yixiang Han,Jianbo Wu,Laixi Bi,Shudao Xiong,Shenmeng Gao,Lihui Yin,Lei Jiang,Chiqi Chen,Kang Yu,Shenghui Zhang

Long-Term Infection and Vertical Transmission of a Gammaretrovirus in a Foreign Host Species

Toshie Sakuma, Jason M. Tonne, Jessica A. Malcolm, Tayaramma Thatava, Seiga Ohmine, Kah-Whye Peng, Yasuhiro Ikeda

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