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OALib Journal期刊
ISSN: 2333-9721
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主页: https://journals.plos.org/plosgenetics/

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Functional Diversity of Carbohydrate-Active Enzymes Enabling a Bacterium to Ferment Plant Biomass

Adriana Alberti,Andrew C. Tolonen,Jean Weissenbach,Magali Boutard,Marcel Salanoubat,Pierre-Yves Nogue,Tristan Cerisy

Epistatic Adaptive Evolution of Human Color Vision

Ahmet Altun,Davide Faggionato,Jinyi Xing,Shozo Yokoyama,William T. Starmer,Yang Liu

Local and Systemic Regulation of Plant Root System Architecture and Symbiotic Nodulation by a Receptor-Like Kinase

Carole Laffont,Emeline Huault,Florian Frugier,Gérard Duc,Jiangqi Wen,Kirankumar S. Mysore,Pascal Ratet

Correction: Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets

The PLOS Genetics Staff

Plasmid Flux in Escherichia coli ST131 Sublineages, Analyzed by Plasmid Constellation Network (PLACNET), a New Method for Plasmid Reconstruction from Whole Genome Sequences

Azucena Mora,Fernando de la Cruz,Jorge Blanco,M. Pilar Garcillán-Barcia,María de Toro,Teresa M. Coque,Val F. Lanza

Correction: Pseudoautosomal Region 1 Length Polymorphism in the Human Population

The PLOS Genetics Staff

ATPase-Independent Type-III Protein Secretion in Salmonella enterica

Florian D. Fabiani,Kelly T. Hughes,Marc Erhardt,Max E. Mertens

DNA Repair Pathway Selection Caused by Defects in TEL1, SAE2, and De Novo Telomere Addition Generates Specific Chromosomal Rearrangement Signatures

Christopher D. Putnam,Katielee Pallis,Richard D. Kolodner,Tikvah K. Hayes

Cancer Evolution Is Associated with Pervasive Positive Selection on Globally Expressed Genes

Esti Yeger-Lotem,James DeGregori,Ruth Barshir,Ruth Hershberg,Sheli L. Ostrow

Loss of Histone H3 Methylation at Lysine 4 Triggers Apoptosis in Saccharomyces cerevisiae

Anja Matter,Birthe Fahrenkrog,David Walter

An Intronic microRNA Links Rb/E2F and EGFR Signaling

Abul B. M. M. K. Islam,James Lightfoot,Mary Truscott,Maxim V. Frolov,Núria López-Bigas

8.2% of the Human Genome Is Constrained: Variation in Rates of Turnover across Functional Element Classes in the Human Lineage

Chris M. Rands,Chris P. Ponting,Gerton Lunter,Stephen Meader

A Central Role for GRB10 in Regulation of Islet Function in Man

Aarno Palotie,Adam Barker,Alan R. Shuldiner,Alena Stan？áková,Andrea Mari,Anke T？njes,Ann-Christine Syv？nen,Anne U. Jackson,Ashish Kumar,Benjamin F. Voight,Bo Isomaa,Cecile Lecoeur,Charlotte Ling,Claire Levy-Marchal,Claudia Langenberg,Clive Osmond,Elisabeth Widen,Emma Ahlqvist,Erik Ingelsson,Hyun Min Kang,Inga Prokopenko,Jalal Taneera,Jari Lahti,Jeffrey R. O'Connell,Jie Liu,Joao Fadista,Johan G. Eriksson,Johanna Kuusisto,Karin Hansson,Ken K. Ong,Kristi D. Silver,Leif Groop,Mark I. McCarthy,Mark Walker,Markku Laakso,Michael N. Weedon,Michael Stumvoll,Nabila Bouatia-Naji,Nicholas J. Wareham,Nils Wierup,Ola Hansson,Paul A. Blomstedt,Peter Almgren,Peter Kovacs,Peter Nilsson,Peter Osmark,Philippe Froguel,Rainer Rauramaa,Rashmi Prasad B,Reedik M？gi,Ruth J. F. Loos,S. Albert Salehi,Sami Alkayyali,Tasnim Dayeh,Tiinamaija Tuomi,Timo A. Lakka,Timothy M. Frayling,Tove Fall,Valeriya Lyssenko,Vasiliki Lagou,Vincent Vatin,Weijia Xie,Wenny Poon,Yu-Ching Cheng

RNA Editome in Rhesus Macaque Shaped by Purifying Selection

Bertrand Chin-Ming Tan,Chu-Jun Liu,Chuan-Yun Li,Huaying Fang,Jia-Yu Chen,Minghua Deng,Mingming Shi,Rongli Zhang,Xin-Zhuang Yang,Xiuqin Zhang,Yong E. Zhang,Zhi-Qiang Ye,Zhiyu Peng

SAS-1 Is a C2 Domain Protein Critical for Centriole Integrity in C. elegans

Fernando R. Balestra,Graham Knott,Lukas von Tobel,Marie Delattre,Pierre G？nczy,Simon Blanchoud,Susanne Finger,Tamara Mikeladze-Dvali,Thomas Müller-Reichert

Fungal Communication Requires the MAK-2 Pathway Elements STE-20 and RAS-2, the NRC-1 Adapter STE-50 and the MAP Kinase Scaffold HAM-5

Anne Dettmann,Oliver Valerius,Sarah Ludwig,Stephan Seiler,Yvonne Heilig

A Systems Genetics Approach Identifies CXCL14, ITGAX, and LPCAT2 as Novel Aggressive Prostate Cancer Susceptibility Genes

Abdel Elkahloun,Alfredo A. Molinolo,J. Silvio Gutkind,Jonathan Andreas,Kendra A. Williams,Minnkyong Lee,Nigel P. S. Crawford,Peter Chines,Settara Chandrasekharappa,Shashank J. Patel,Suiyuan Zhang,Ying Hu

The Coding and Noncoding Architecture of the Caulobacter crescentus Genome

Bo Zhou,Brandon Williams,Gene-Wei Li,Harley H. McAdams,Jared M. Schrader,Jonathan S. Weissman,Keren Lasker,Lucy Shapiro,Sean Crosson,Tao Long,W. Seth Childers

Loss and Recovery of Genetic Diversity in Adapting Populations of HIV

John Wakeley,Pleuni S. Pennings,Sergey Kryazhimskiy

Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease

Aarno Palotie,Ad R. Hermus,Alan James,Albert Hofman,Albert de la Chapelle,Alec Ross,Alessandro Delitala,Alexander Hamilton,Alexander Kluttig,Alexander Teumer,Alexandra P. Bremner,Alice Arnold,Allan Linneberg,Andrew T. Hattersley,André G. Uitterlinden,Anne Cappola,Antonella Mulas,Betina Thuesen,Beverley M. Shields,Bijay Vaidya,Bruce M. Psaty,Christa Meisinger,Christian Gieger,Christin Spielhagen,Cinzia Sala,Corrado Masciullo,Daniel Tiller,Daniela Toniolo,David I. W. Philips,David Schlessinger,Diana Pietzner,D？rte Radke,Ee M. Lim,Eero Kajantie,Eleonora Porcu,Elisabeth Widen,Emanuele Bosi,Eric Wichmann,Ernst E. Rietzschel,Eva Reischl,Fernando Rivadeneira,Fred C. Sweep,Gabriela L. Surdulescu,Georg Homuth,Giorgio Pistis,Goncalo Abecasis,Greet L. Roef,Hans J？rgen Grabe,Henri Wallaschofski,Henriette Meyer zu Schwabedissen,Henry V？lzke,Holger Prokisch,Huiling He,J. Brent Richards,Jari Lahti,Jayne A. Franklyn,Jean-Marc Kaufman,Jennie Hui,Jerome I. Rotter,Johan G. Eriksson,Johannes W. A. Smit,John P. Beilby,John P. Walsh,Jürgen Kratzsch,Katharina Schramm,Katri R？ikk？nen,Lambertus A. Kiemeney,Layal Chaker,Linda Broer,Lise Lotte N. Husemoen,Marco Medici,Margit Heier,Maria Grazia Plia,Martijn van de Bunt,Martin den Heijer,Massimiliano Cocca,Matteo Vocale,Matthew J. Simmonds,Matthias Nauck,Michela Traglia,Monia Lobina,Nicola Pirastu,Nicole Soranzo,Peter C. O'Leary,Peter Feddema,Peter J. Leedman,Rachel M. Freathy,Rajesh Rawal,Rebecca Nagy,Richard A. Jensen,Robin P. Peeters

The Challenges of Mitochondrial Replacement

Douglass M. Turnbull,James B. Stewart,Lyndsey Craven,Mary Herbert,Patrick F. Chinnery,Shoukhrat Mitalipov

3′ Untranslated Regions Mediate Transcriptional Interference between Convergent Genes Both Locally and Ectopically in Saccharomyces cerevisiae

Lin Wang,Lindsey J. Leach,Luwen Wang,Ning Jiang,Ou Fang,Xiaohua Hu,Zewei Luo

FGFR1-Frs2/3 Signalling Maintains Sensory Progenitors during Inner Ear Hair Cell Formation

Kazuya Ono,Kiyoshi Kawakami,Marie Paschaki,Masataka Ito,Noriko Gotoh,Paul O'Neill,Raj K. Ladher,Shigeru Sato,Siu-Shan Mak,Tomoko Kita,Yoshiki Sasai

Knock-In Reporter Mice Demonstrate that DNA Repair by Non-homologous End Joining Declines with Age

Amita Vaidya,Andrei Seluanov,Brianna Spencer,Vera Gorbunova,Xiao Tian,Zhiyong Mao

Comparative Phylogenomics Uncovers the Impact of Symbiotic Associations on Host Genome Evolution

Gloria M. Coruzzi,J. Chris Pires,Jean-Michel Ané,Kranthi Varala,Patrick P. Edger,Pierre-Marc Delaux

Phenotype Ontologies and Cross-Species Analysis for Translational Research

Caleb Webber,Peter N. Robinson

Concocting Cholinergy

Artur Kania

The Red Queen Model of Recombination Hotspots Evolution in the Light of Archaic and Modern Human Genomes

Dominique Mouchiroud,Laurent Duret,Nicolas Lartillot,Sylvain Glémin,Yann Lesecque

Three RNA Binding Proteins Form a Complex to Promote Differentiation of Germline Stem Cell Lineage in Drosophila

Chan Wu,Di Chen,Qing Geng,Shaowei Zhao,Xin Li,Yang Zhang,Yu Gao,Zhaohui Wang

An Essential Nonredundant Role for Mycobacterial DnaK in Native Protein Folding

Allison Fay,Michael S. Glickman

Genetic Analysis of a Novel Tubulin Mutation That Redirects Synaptic Vesicle Targeting and Causes Neurite Degeneration in C. elegans

Albert Lee,Chun-Hao Chen,Chun-Liang Pan,Gian Garriga,Jiun-Min Hsu,Kent L. McDonald,Mark Gurling,Yen-Chih Chen

Correction: Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer’s Disease and Related Dementias

The PLOS Genetics Staff

Genome-Wide Patterns of Genetic Variation within and among Alternative Selective Regimes

Aneil F. Agrawal,Stephen I. Wright,Yuheng Huang

A System for Genome-Wide Histone Variant Dynamics In ES Cells Reveals Dynamic MacroH2A2 Replacement at Promoters

Christopher J. Lengner,Jui-Hung Hung,Oliver J. Rando,Ozlem Yildirim,Ryan J. Cedeno,Zhiping Weng

Hypoxia Adaptations in the Grey Wolf (Canis lupus chanco) from Qinghai-Tibet Plateau

Bisong Yue,Eunjung Han,Hong Liu,Jie Huang,John P. Pollinger,Liang Zhang,Lianming Du,Marco Galaverni,Pedro Silva,Peng Li,Robert K. Wayne,Rong Hou,Wenping Zhang,XiuyYue Zhang,Zhenxin Fan,Zhihe Zhang

Ras GTPase-Like Protein MglA, a Controller of Bacterial Social-Motility in Myxobacteria, Has Evolved to Control Bacterial Predation by Bdellovibrio

Andrew L. Lovering,David S. Milner,Emma B. Saxon,Ian Cadby,Laura E. Williams,R. Elizabeth Sockett,Rob Till,Sarah M. Basford,Susan Liddell

Methylome Diversification through Changes in DNA Methyltransferase Sequence Specificity

Hiroe Namba-Fukuyo,Ichizo Kobayashi,Mitsuyasu Hasebe,Shuji Shigenobu,Sumio Sugano,Tomoaki Nishiyama,Tomoko F. Shibata,Yoshikazu Furuta,Yutaka Suzuki

Cell Type-Specific Functions of Period Genes Revealed by Novel Adipocyte and Hepatocyte Circadian Clock Models

Andrew C. Liu,Chidambaram Ramanathan,David K. Welsh,Haiyan Xu,John B. Hogenesch,Paula J. Gitis,Sanjoy K. Khan,Yang Shen

The Rate of Nonallelic Homologous Recombination in Males Is Highly Variable, Correlated between Monozygotic Twins and Independent of Age

Jacqueline A. L. MacArthur,Kerrin S. Small,Massimo Mangino,Matthew E. Hurles,Raj Gill,Sarah J. Lindsay,Timothy D. Spector

Bacterial Regulon Evolution: Distinct Responses and Roles for the Identical OmpR Proteins of Salmonella Typhimurium and Escherichia coli in the Acid Stress Response

Andrew D. S. Cameron,Charles J. Dorman,Heather J. Quinn

Correction: Selection on a Variant Associated with Improved Viral Clearance Drives Local, Adaptive Pseudogenization of Interferon Lambda 4 (IFNL4)

The PLOS Genetics Staff

Trans-kingdom Cross-Talk: Small RNAs on the Move

Hans Thordal-Christensen,Maria E. Constantin,Marijn Knip

The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy

Alexander J. Whitworth,Alvaro Sanchez-Martinez,Emma Wilson,Heather Mortiboys,Joe H. Pogson,Rachael M. Ivatt,Roberta Tufi

Correction: Controlling Meiotic Recombinational Repair – Specifying the Roles of ZMMs, Sgs1 and Mus81/Mms4 in Crossover Formation

The PLOS Genetics Staff

tRNA Modifying Enzymes, NSUN2 and METTL1, Determine Sensitivity to 5-Fluorouracil in HeLa Cells

Achim Temme,Fumio Shimamoto,Futoshi Yazama,Guangying Qi,Hiroaki Konishi,Kaoru Okada,Mamoru Fujiwara,Masaaki Tatsuka,Masato Hori,Mayumi Okamoto,Takahide Ota,Yegui Xiao

Role for Circadian Clock Genes in Seasonal Timing: Testing the Bünning Hypothesis

Charalambos P. Kyriacou,Eran Tauber,Joao S. Gesto,Mirko Pegoraro

SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene

Anusha Sridharan,Jeffrey A. Whitsett,Logan Fulford,Mario Medvedovic,Markaisa Black,Tanya V. Kalin,Tien Le,Vladimir Ustiyan,Vladimir V. Kalinichenko,Xin-Hua Cheng

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