Tobacco smoke contains mutagenic chemicals that are in the “probably carcinogenic” or “possibly carcinogenic” categories. In addition to free radicals, cigarette smoke is also rich in combustion toxic gases that can reach a very high concentration and become involved in more radical formation. Tobacco smoke contains a mixture of chemicals, including a host of reactive oxygen species (ROS), among others, that can damage cellular and sub-cellular targets, such as lipids, proteins, and nucleic acid...

Oncology  Biochemistry 

Doi:-

Population-scale and rapid testing for SARS-CoV-2 continues to be a priority for several parts of the world. We revisit the in vitro technology platforms for COVID-19 testing and diagnostics—molecular tests and rapid antigen tests, serology or antibody tests, and tests for the management of COVID-19 patients. Within each category of tests, we review the commercialized testing platforms, their analyzing systems, specimen collection protocols, testing methodologies, supply chain logistics, and rel...

Allergy & Clinical Immunology  Electrochemistry  Information Technologies  Medical Education  Biological Chemistry  Virology  Medicinal Chemistry  Developmental Biology  Environmental Sciences  Biological Engineering  Genomics  Genetics  Food Science & Technology  Marketing  Oncology  Technology And Innovation  Theoretical Chemistry  Diagnostics  Supply Chain Management  Biological Materials  Nanometer Materials  Drugs & Devices  Public Health  Organic Chemistry  Epidemiology  Sales Management  Molecular Biology  Health Policy  Microbiology  Global Health  Bioengineering  Physical Chemistry  Bioinformatics  Biotechnology  Functional Materials  Computational Biology  Cell Biology  Parasitology  Translational Medicine  Infectious Diseases  Women’s Health  Immunology  Respiratory Medicine  Materials Engineering  Internal Medicine  Metabolic Sciences  Medical Genetics 

Doi:10.3390/s21196581

Over the years, several tumor biomarkers have been suggested to foresee the prognosis of oral squamous cell carcinoma (OSCC) patients. Here, we present a systematic review to identify, evaluate and summarize the evidence for OSCC reported markers. Eligible studies were identified through a literature search of MEDLINE/PubMed until January 2016. We included primary articles reporting overall survival, diseasefree survival and cause specific survival as outcomes. Our findings were analysed using R...

Histology  Dentistry  Oncology  Pathology 

Doi:10.1016/j.oraloncology.2017.07.003

Introduction: Hepatitis C is the first aetiologic agent for HCC in Morocco. Antiviral treatment reduces the risk of developing HCC in patients with chronic hepatitis C but few cases of HCC have been still reported. We aimed to define population with high risk of HCC occurrence, confirm the protective role of SVR and to identify predictive factors of developing HCC after SVR. We’ll try to present suggestions about screening strategies (indications and interval) after antiviral therapy according t...

Public Health  Virology  Gastroenterology & Hepatology  Oncology  Infectious Diseases 

Tumour metastasis refers to the spread of cancer cells from the initial site of primary tumor to a distant secondary location. Cancerous tumor usually possesses a very large number of cells with genetic mutations which motivate them to grow, proliferate, and then, invade the local surrounding tissues. As the tumor grows larger, some of the cells are dislodged from the main tumor and carried away by the blood or lymphatic vessels. These "circulating tumor cells" or CTCs possess important informat...

Oncology 

Doi:10.15562/tcp.2

Introduction: Liposarcomas are considered the most common type of soft tissue sarcoma in adults. They represent approximately 20% of all mesenchymal malignancies and most frequently involve the retroperitoneum, trunk and extremities. Hypopharyngeal localisation of a liposarcoma is extremely rare. To determine the prevalence of liposarcomas of the hypopharynx, we conducted a systematic review of the literature. Methods: We performed a systematic search of the literature until 2015 using PubM...

Oncology  Otorhinolaryngology 

Doi:10.19204/2016/lpsr8