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Malignant Melanoma of Unknown Primary Site Simulating A Salivary Gland Neoplasm
Kiran AGARWAL,Sonal JAIN,Jasmita DASS,Manoj ANDLEY
Türk Patoloji Dergisi , 2011,
Abstract: Malignant melanoma with its varied clinical presentations and histomorphological patterns is a perplexing problem both for the diagnosticians and clinicians. A small proportion of melanomas present with metastatic tumors with unknown primary sites and at these sites they mimic the more common primary neoplasms. We hereby report a case of malignant melanoma presenting as a submandibular lump in a 40 year old female. This lump was present for six months and was rapidly increasing in size. On cytology it was diagnosed as salivary gland neoplasm.
Clinicopathological study of salivary gland tumors: an assessment of 303 patients
Morais, Maria de Lourdes Silva de Arruda;Azevedo, Paulo Roberto;Carvalho, Cyntia Helena;Medeiros, Lélia;Lajus, Tirzah;Costa, Antonio de Lisboa Lopes;
Cadernos de Saúde Pública , 2011, DOI: 10.1590/S0102-311X2011000500020
Abstract: salivary gland neoplasms are remarkable for their histological diversity and several studies point to their varied occurrence in the population. clinical aspects were histologically assessed to determine possible associations and define parameters to differentiate benign and malignant neoplasms. the case files of patients diagnosed with epithelial salivary gland tumors between 1989 and 2005 were reviewed. a majority (71%) of the 303 salivary gland tumors studied were benign and pleomorphic adenoma were found to be most common. mean ages for patients with benign and malignant tumors were 49.2 and 58.5 years, respectively. a statistically significant difference between these tumors was observed for the following variables: mean age, tumor size and disease duration. a correlation was found between histological diagnosis and tumor consistency. the data presented here corroborate a number of previous studies and are therefore relevant in understanding the diverse characteristics exhibited by these tumors.
Tumores de glándulas salivales: Nuestra experiencia
Pérez Abreus,Enrique; Ordú？ez García,Pedro; Cruz Leyva,ángel Luis;
Revista Cubana de Estomatolog？-a , 2000,
Abstract: an applied descriptive and longitudinal investigation was made with all the patients carriers of salivary gland tumors that needed surgical treatment at the maxillofacial surgery service of "dr. gustavo aldereguía" clinical and surgical teaching hospital, in cienfuegos, from january, 1990, to december, 1999. it was observed a predominance of females as well as of the age group over 60. the parotid gland was the most affected, whereas the pleomorphic salivary adenoma was the commonest. the adenoid cystic carcinoma was the most frequent in the group of carcinomas. surgery was the main treatment used, followed by the surgical-radiant combination. some drug therapy schemes were also analyzed.
Patología quirúrgica de glándulas salivales: Reporte de 79 casos
Pérez Abreus,Enrique; González Domínguez,Nurelys;
Revista Cubana de Estomatolog？-a , 1999,
Abstract: we made an updated review on surgical pathology of major salivary glands and to present results pobtained for 7 years of experience, from january 1990 to december 1996 in 79 patients presentig with this pathology in "dr. gustavo aldereguía" teaching clinical surgical hospital of cienfuegos province. different inflammatory, lithiasic and tumoral processes of salivary glands as well as therapeutics used were analyzed. mean age was 50.7 years with a predominance of female sex; commonest pathology was tumoral type including adenomas (52 %), followed by relate injuries (29.1 %), and carcinomas (10.2 %). surgery alone or combined with others procedures were main cornerstones of treatment.
Mucoepidermoid carcinoma of the soft palate salivary gland.
Syed Zaifullah SYED HAMZAH,Mohd Razif MOHAMAD YUNUS
Brunei International Medical Journal , 2012,
Abstract: Mucoepidermoid carcinoma is a malignant epithelial tumour of glandular tissue, usually of the major salivary glands. However it can present in the minor salivary glands, especially in the soft palate. We report the case of a 72-year-old Malay female after presentation with sore throat, fever and odynophagia, was diagnosed with mucoepidermoid carcinoma of the soft palate.
Minor salivary gland tumors in a south American population
Concei？？o Barros Adna,Gurgel Silva Araújo Clarissa,Gomes Caymmi Mário,Agra Gon？alves Marcelo Ivan
Archive of Oncology , 2010, DOI: 10.2298/aoo1003056c
Abstract: Background: Salivary gland tumors are uncommon. This study aimed to investigate both clinical and epidemiological aspects of minor salivary gland tumors in a Brazilian population. Methods: From 1976 to 2007, data obtained from clinical records and histological diagnoses were reviewed according to the WHO. Results: A total of 217 MSGTs were identified. Pleomorphic adenomas (83%) and adenoid cystic carcinomas (28.8%) were the most frequent ones. The mean age of patients with benign and malignant tumors was 54.7 and 44.7 years, respectively. There was a female predominance and the palate was the most affected location. Surgery was the treatment of choice, but adjuvant radiotherapy and/or chemotherapy were also used. Recurrence rate of benign and malignant tumors was respectively 11.2% and 20.4%. Conclusion: this population showed a relatively higher proportion of malignant tumors, and these tumors were associated with a higher rate of recurrence when compared to benign tumors. However, the overall recurrence of 16.2% was also within the reported range for these tumors. In addition, despite the results of this study are similar to previous series found in the literature, it provides an important insight into the epidemiology of patients presenting minor salivary gland tumors.
Pleomorphic adenoma with extensive squamous metaplasia and keratin cyst formations in minor salivary gland: a case report
Goulart, Maria Carolina Vaz;Freitas-Faria, Patrícia;Goulart, Gláuter Rodrigues;Oliveira, Adriano Macedo de;Carlos-Bregni, Roman;Soares, Cleverson Teixeira;Lara, Vanessa Soares;
Journal of Applied Oral Science , 2011, DOI: 10.1590/S1678-77572011000200016
Abstract: pleomorphic adenoma (pa), the most common salivary gland tumor, accounts for 54 to 65% of all salivary gland neoplasias and 80% of the benign salivary gland tumors. it most frequently affects the parotid gland, followed by the submandibular and the minor salivary glands. microscopically, mucous, sebaceous, oncocytic and squamous metaplasia, sometimes with the formation of keratin pearls, may be present, but the latter rarely results in the formation of extensive keratin-flled cysts lined by squamous epithelium. extensive squamous metaplasia can be mistaken for malignancy, including mucoepidermoid carcinoma and squamous cell carcinoma. here, we present an unusual case of pa with extensive squamous metaplasia and keratin cyst formations in a minor salivary gland, and discuss its microscopic features, including the immunohistochemical characteristics, and differential diagnosis of this uncommon presentation.
Perfil epidemiológico das neoplasias de glandulas salivares: análise de 245 casos
Lima, Solange Souza;Soares, Andréa Ferreira;Amorim, Rivadávio Fernandes Batista de;Freitas, Roseana de Almeida;
Revista Brasileira de Otorrinolaringologia , 2005, DOI: 10.1590/S0034-72992005000300012
Abstract: aim: the aim of the present study is to establish the relative frequency and distribution of benign and malignant epithelial neoplasms of salivary glands in the pathology and cytology laboratory, study design: historic cohort. material and method: in the state of sergipe, during the period 1980-1999. the neoplasms were individualized by gender, age, race of the patients, anatomic localization of the lesions and histopathological diagnosis. results: out of 162,312 registered cases, 245 were salivary gland epithelial neoplasms and 187 (76.33%) were benign and 58 (23.67%) were malignant. pleomorphic adenoma was the most frequent benign neoplasm (89.94%) and adenoid cystic carcinoma represented the most prevalent malignant neoplasm (22.41%). the benign neoplasms occurred mainly between the second and third decades of life and showed preference for female, while malignant neoplasms were diagnosed between the sixth and seventh decades of life and in women. conclusion: the data demonstrated that epidemiology profile of the studied neoplasms corroborated most of the studied literature.
Biopsia por aspiración con aguja fina en el diagnóstico de lesiones de glándula salival
GUTIéRREZ M,NESTOR; MORA,VERóNICA; REIGOSA,ALDO; CALEIRAS,EDUARDO; BAEZ,EORIS; BRICE？O,ALEJANDRO; RAMOS,SILVIA; ,;
Revista Venezolana de Oncología , 2007,
Abstract: objetivos: the benign and wicked pathologies of the salivary gland are bound to the characteristic anatomopatologic, which are in permanent revision and whose classification is controversial. the cytology for punction with fine needle it has arisen minimamly as a technique invasive of diagnose tumorous lesions. the utility of the fine needle aspiration puntion has demonstrated to be a method, cheap, sensitive, specify for diagnose of tumour and lesions non tumours and it allows distinguishing surgical cases of not surgical. methods: one carries out a descriptive, retrospective, traverse and observational study. 47 histories were revised with diagnose clinical of lesion in salivary gland; the available histological discoveries were revised in 33 cases to establish the correlation citohistologic. results: of 47 patients to which are carried out aspired 11 were inadequate and 36 enough or appropriate, inflammatory 3 cases. benign primary neoplasms was 23 patients of which 17 corresponded to adenoma pleomorphic. 6 cases were wicked epithelial neoplasms, 1 neoplasms lymphoid and 2 neoplasms metastasic. conclusions: fine needle aspiration of salivary gland is a method that helps distingue benign lesions of wicked, primary of metastatic, in this sense pursues, and often allows, to settle down if it is or not of a tumors process, and in this last case, to determine the benign or wicked nature of the same one, its primary or secondary character, facilitating this way an appropriate selection of this salivary pathology in a sense medical o surgery.
Quality of life in patients submitted to surgical treatment for minor salivary gland neoplasms
Hirota, Sílvio Kenji;Penha, Sibele Sarti;Lehn, Carlos Neutzling;Sugaya, Norberto Nobuo;Migliari, Dante Ant？nio;
Brazilian Oral Research , 2007, DOI: 10.1590/S1806-83242007000400016
Abstract: this study was aimed at assessing the quality of life in patients submitted to surgical treatment for minor salivary gland neoplasms (msgn). twelve patients (10 women and 2 men, mean age: 49.4 years) with histopathologic diagnosis of pleomorphic adenoma (pa, 3 cases), polymorphous low-grade adenocarcinoma (plga, 2 cases), cystic adenoid carcinoma (cac, 4 cases), and muco-epidermoid carcinoma (mec, 3 cases) were evaluated. all of them were treated by surgical excision; patients with cac received radiotherapy as well. the patients’ quality of life was evaluated through a self-administered questionnaire concerning their physical well-being, emotional status, normal daily activities, and family relationships. the results showed that patients with mec - the youngest among all patients - reported a significantly greater worsening of their physical well-being and emotional status after treatment as compared with patients treated for pa (p < 0.05), and also of their functional activities as compared with those treated for pa and plga (p < 0.05). in conclusion, age of development of the neoplasm and type of disease produce more impact on patients’ quality of life than does the therapy’s degree of aggression.
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