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OALib Journal期刊

ISSN: 2333-9721

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Ocular Adnexal Lymphoma Presenting with Visual Loss
Nagla Karim,Shuchi Gulati,Stephen Medlin,Zélia M. Corrêa
- , 2016, DOI: 10.4103/1947-2714.175217
Abstract: Elderly patients with visual loss often have age-related macular degeneration, diabetic retinopathy, glaucoma, and cataract as common causes of visual loss. Other less common etiologies should be considered, especially in those presenting with systemic associations
Role of Chlamydia in the Development of Ocular Adnexal Lymphoma  [PDF]
Carlo Contini, Silva Seraceni, Martina Maritati, Francesco Cavazzini, Paolo Perri
Journal of Cancer Therapy (JCT) , 2013, DOI: 10.4236/jct.2013.42082
Abstract:

The aetiology of OAL is undefined, although much attention has been recently focused on determining whether OAL is caused by an autoimmune disorder, chronic antigenic stimulation or both. It is becoming evident that infectious agents underlying chronic eye infection, as Chlamydia, may play a role in ocular lymphomagenesis. The high prevalence of Chlamydophila psittaci in patients with OAL has suggested a potential oncogenic role for its tendency to cause chronic and persistent infections, although it has been documented an evident geographical variability and response to antibiotic treatment. For C. pneumoniae, the findings so far obtained are very limited not only for identification in OAL but also for the specific treatment with antibiotics. The recent molecular and cultural evidence of C. trachomatis in patients with OAL, seems to suggest that also this pathogen may contribute to pathogenesis of such lymphoma. The potential application of bacteria-eradicating therapy at local and systemic level may ultimately result in safer and more efficient therapeutic option for patients affected by these malignancies. Moreover, a close collaboration between experts in ophthalmology, infectious diseases and hematology will help, in the future, to effectively manage this disease. This review attempts to weigh the currently available evidence regarding the role that Chlamydia play in development of OAL and focuses on patients with OAL observed at our Institution.

Choroidal Lymphoma Discovered on Ultrasound in a Patient with Suspected Corneal Tumor
Andrew A. Kao,Armin R. Afshar,Bertil E. Damato,Christos Theophanous,Jay M. Stewart,Melike Pekmezci,Michele M. Bloomer
- , 2018, DOI: 10.1159/000486039
Abstract: To report the case of a 77-year-old male with a blind, painful eye, referred for suspected corneal mass, with finding of choroidal B-cell lymphoma on pathology of enucleated globe
Orbital plasmablastic lymphoma: a clinico-pathological correlation of a rare disease and review of literature
Mulay K, Ali MJ, Reddy VA, Honavar SG
Clinical Ophthalmology , 2012, DOI: http://dx.doi.org/10.2147/OPTH.S38282
Abstract: bital plasmablastic lymphoma: a clinico-pathological correlation of a rare disease and review of literature Case Series (1194) Total Article Views Authors: Mulay K, Ali MJ, Reddy VA, Honavar SG Published Date December 2012 Volume 2012:6 Pages 2049 - 2057 DOI: http://dx.doi.org/10.2147/OPTH.S38282 Received: 18 September 2012 Accepted: 23 October 2012 Published: 11 December 2012 Kaustubh Mulay,1 Mohammad Javed Ali,2 Vijay Anand Reddy,2 Santosh G Honavar2 1Ocular Pathology Service, LV Prasad Eye Institute, Hyderabad, Andhra Pradesh, India; 2Oncology Service, LV Prasad Eye Institute, Hyderabad, Andhra Padresh, India Abstract: Ocular involvement by plasmablastic lymphoma is extremely rare with very few reports in the literature. Its morphological and immunological resemblance to plasma cell myeloma makes it a diagnostic challenge, while its clinical course, which is characterized by recurrence and death, makes therapy a challenge for clinicians. We present three cases of plasmablastic lymphoma, each of which has distinct clinicoradiological features, and we also review the literature on orbital plasmablastic lymphomas.
Relapsed Burkitt Lymphoma Presenting as an Isolated Infiltrative Optic Neuropathy
Joshua K. Fernandes,Manjot K. Gill,Shiraaz I. Rahman
- , 2016, DOI: 10.3109/01658107.2016.1153113
Abstract:
Experiencia de 10 a？os en linfomas oculares y de anexos oculares
Caballero-Caballero, Rocío;Hernández-Rivera, E.Gabriela;López-Karpovitch, Joseph X.;
Gaceta médica de México , 2006,
Abstract: background. ocular lymphomas and ocular adnexae lymphomas (ol and o al) constitute 7-8% of all extranodal lymphomas. objective. describe the clinical, morphologic and immunophenotypic characteristics of oal seen in our hospital. material and methods. retrospective analysis of patient records with ol and oal between july 1994 and july 2005. the following data was analyzed: clinical presentation, therapy, treatment response, overall survival and disease free survival. results. ten patientswith ol and oal were identified. of these, 8 were women and 2 men. median age was 50. eight of 10 patients achieved complete remission, 6 of the 6 presenting malt lymphoma. two patients with stage iv had refractory disease. conclusions. in our series 0.02% of lymphomas were ol and oal of a total 498 lnh. malt lymphomas appear at a more advanced age, sixty percent of the cases were malt lymphomas and were diagnosed during their early stages. patients were followed during 21 months, global survival was 100%, free illness survival had a mean of 868 days and a survival median of 442 days.
Ocular non-Hodgkin lymphoma: a report of two cases and review of the literature
Mediscope , 2018, DOI: https://doi.org/10.3329/mediscope.v5i2.37147
Abstract: In this article, two cases of non-Hodgkin lymphomas (NHL) occurring at an unusual site were reported. The first case was a male patient aged 60 years hailing from Debidwar, Comilla came with the complaint of gradually increasing mass in the left eyelid for two years. Fine-needle aspiration (FNA) and histopathology of his lesion revealed NHL, which on immunohistochemistry showed to be of B-cell origin. A debulking operation was done in National Institute of Ophthalmology & Hospital, Dhaka and he was sent for chemotherapy. The second case was also a male aged 35 years from Muladi, Barisal who presented with gradually increasing bilateral masses on both the upper eyelids for six months. The results of FNA of the eyelid tumors were suggestive of NHL that was subsequently confirmed by histopathology. Immunohistochemistry showed the tumor to be of B-cell origin. Mediscope Vol. 5, No. 2: Jul 2018, Page 36-41
A Primary Bone Diffuse Large B-Cell Lymphoma with Ocular Adnexal Involvement
Ceyda Aslan,Cihan Gündo？an,Elif Suyan？,Mehmet Hilmi Do？u,Osman Yoku？,Rafet Eren
- , 2016, DOI: 10.4274/tjh.2015.0424
Abstract:
眼结膜MALT淋巴瘤1例并文献复习
One Case of Conjunctival MALT Lymphoma and Literature Review  [PDF]
李旭霞, 林丽莉, 段小钰, 王慧霞, 曾璐, 曹雷, 赵爽彦, 扈婷婷, 蔡宏懿
Advances in Clinical Medicine (ACM) , 2022, DOI: 10.12677/ACM.2022.1281095
Abstract: 目的：探讨眼结膜MALT淋巴瘤的放疗剂量及放疗后并发症的管理。方法：回顾性分析该院收治的1例眼结膜MALT淋巴瘤患者的临床资料，并结合国内外文献进行复习探讨。结果：患者以左眼结膜黄豆粒大小的新生肿物为主要临床表现，于外院行手术切除，术后病检示黏膜相关淋巴组织结外边缘区淋巴瘤。后患者行左眼调强放疗，剂量：95% PTV，30 Gy/2 Gy/15 F，放疗后随访1个月未见肿瘤复发、转移，患者诉眼干，余无特殊不适。结论：眼结膜MALT淋巴瘤临床较罕见，放射治疗疗效确切、并发症可控。
Objective: To investigate the dose of radiotherapy and the management of post-radiotherapy com-plications in conjunctival MALT lymphoma. Methods: The clinical data of a patient with conjunctival MALT lymphoma admitted to the hospital were retrospectively analyzed, and reviewed and dis-cussed with domestic and international literature. Results: The patient presented with a neoplastic mass the size of a soybean grain in the left conjunctiva as the main clinical manifestation and un-derwent surgical resection at an outside hospital. Postoperative pathological examination showed lymphoma in the extra-nodal marginal zone of mucosa-associated lymphoid tissue. The patient was treated with intensity-modulated radiotherapy in the left eye at a dose of 95% PTV, 30 Gy/2 Gy/15 F, and no tumor recurrence or metastasis was observed in the 1-month follow-up after radiotherapy. Conclusion: Conjunctival MALT lymphoma is rare clinically, and the efficacy of radiation therapy is precise and the complications are manageable.
Linfomas de la órbita y anexos oculares: Correlación clínico patológica de 25 casos
Rojas Bilbao,Erica A.; Nesprias,Martina; Pulero,Carla; Giménez,Liliana; Zerga,Marta; Chirife,Ana María;
Medicina (Buenos Aires) , 2010,
Abstract: clinical, histological features and outcome of a cohort of patients with orbital and adnexal lymphoproliferative tumors were evaluated. twenty-five cases in an oncologic referral center from 1995 to 2008, were included in the study. each case had detailed immunophenotypic analysis using a panel of monoclonal antibodies (cd45, cd20, cd3, cd5, cd23, bcl2, bcl6, bcl10, ki67, cd30, cd15, bcl1, kappa, lambda, cd138). lesions were classified by using who (2008) lymphomas classification. twenty-three patients were found to have primary and two secondary lymphomas. histological subtypes were: 16 patients with marginal zone b cell lymphoma of mucosa-associated lymphoid tissue (malt) lymphoma, four diffuse large b cell lymphomas, two mantle cell lymphomas, two follicular lymphomas, and one hodgkin lymphoma. among the 25 patients studied, 22 had localized stage. extranodal marginal zone lymphoma was the most frequent type of primary orbital and adnexal lymphoma. in this study localized disease was observed in most cases, and distant spread of the lymphomas was infrequent.
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