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吴克明教授用新加苁蓉菟丝子汤治疗不孕症临证经验
Professor Wu Keming’s Experience in Treating Infertility with Xinjia Congrong Tusizi Decoction  [PDF]
刘先华, 吴克明
Traditional Chinese Medicine (TCM) , 2026, DOI: 10.12677/tcm.2026.151037
Abstract: 不孕症(Infertility)作为生殖系统功能障碍性疾病，现代医学主要采取对症治疗，但部分患者仍面临妊娠失败等难题。本文介绍名老中医吴克明教授采用中西医结合诊疗不孕症的临证经验。吴克明教授在临床中遵循“先辨病，次辨证，再议法，后议药”的诊疗思路，灵活运用新加苁蓉菟丝子汤，补肾益精、养血活血，改善性激素水平紊乱，促进卵泡健康发育与成熟，延缓生殖系统衰老进程，实现调经助孕目的。
As a disorder of the reproductive system, infertility is primarily managed with targeted medical interventions in modern medicine; however, some patients still experience unresolved challenges, such as recurring pregnancy complications. This article delineates the clinical management experience for infertility developed by Professor Wu Keming, a distinguished TCM expert, through the integration of Chinese and Western medical approaches. Professor Wu Keming follows the diagnostic and treatment approach of “first identifying the disease, then differentiating the syndrome, next determining the therapeutic strategy, and finally tailoring medicinal” in clinical practice. Dynamically employing the Xinjia Congrong Tusizi Decoction, Professor Wu regulates sex-hormone homeostasis through kidney essence replenishment and blood-nourishing/stasis-resolving effects, thereby fostering follicular development/maturation while attenuating reproductive senescence to achieve menstrual-cycle transcription and fertility promotion.
骨碎补、淫羊藿、菟丝子总黄酮对成骨细胞 体外培养影响的比较研究
于向东,秦林林,谢雁鸣,邓文龙,鲍安德
中国中医药信息杂志 , 2005,
Abstract: 目的 骨碎补总黄酮、淫羊藿总黄酮及菟丝子总黄酮对成骨细胞体外培养影响的比较研究。方法 UMA-106-01成骨细胞株进行成骨细胞培养,观察ALP活性和3H-TdR掺入的情况。结果 24 h培养液中骨碎补总黄酮ALP活性高于对照组,P<0.05；细胞内骨碎补总黄酮、淫羊藿总黄酮ALP活性显著增加,与对照组比较,P<0.05或P<0.001。48 h培养液中骨碎补总黄酮、淫羊藿总黄酮、菟丝子总黄酮ALP活性高于对照组,P<0.05或P<0.001；细胞内骨碎补总黄酮、淫羊藿总黄酮、菟丝子总黄酮ALP活性显著增加,与对照组比较,P<0.001。骨碎补总黄酮、淫羊藿总黄酮24 h 3H计数显著高于对照组,P<0.001。结论 3种中药总黄酮对成骨细胞活性的促进作用,以骨碎补总黄酮最为广泛,淫羊藿总黄酮次之,菟丝子总黄酮最差
A Systematic Review on Chemical Constituents of Suanzaoren Decoction, a Traditional Chinese Medicine Prescription  [PDF]
Wenchao Gu, Tianyuan Ye, Liangkun Zhang, Yong Yang, Dongmei Qi, Xiaorui Cheng, Xin Wang
International Journal of Clinical Medicine (IJCM) , 2021, DOI: 10.4236/ijcm.2021.1211045
Abstract: Traditional Chinese Medicine prescription Suanzaoren decoction (SZRD) is composed of Ziziphi Spinosae Semen, Chuanxiong Rhizoma, Anemarrhenae rhizoma, Poria and Licorice. It was used to treat central nervous system diseases such as insomnia and anxiety for thousands of years. This paper aims to systematically understand varieties and quantities of compounds and clarify chemical components of SZRD, subsequently to further provide the reference for phytochemistry and pharmacology researches of SZRD. Our results showed that SZRD contained 145 components, including flavonoids, triterpenoids, steroids, coumarins, phthalides, and volatile oils, etc., while five-single herbs contain 1104 components. Only in terms of compound number, there were 80 common components in SZRD and its five herbs, which accounted for 6.8% of total compounds in all 5 herbs and 55.2% of compounds in SZRD. The components of SZRD were not simply the sum of one in every single herb. It is necessary to perform parallel studies among SZRD and its herbs. This review discussed the problems that existed in the chemical research of SZRD and pointed out the direction for its further research.
《伤寒杂病论》方治验二则
杨军,谭颖颖,陈丽名
中国中医药信息杂志 , 2020,
Abstract: 《伤寒杂病论》方在临床用之得当，则效如桴鼓，尤其治疗疑难病效果更为明显。本文结合二则案例介绍《伤寒杂病论》方在临床中的具体运用，值得借鉴
The Degradation Mechanism of Toxic Atractyloside in Herbal Medicines by Decoction
Liang-Yu Chen,Anren Hu,Chih-Jui Chang
Molecules , 2013, DOI: 10.3390/molecules18022018
Abstract: Atractyloside (ATR) is found in many Asteraceae plants that are commonly used as medicinal herbs in China and other eastern Asian countries. ATR binds specifically to the adenine nucleotide translocator in the inner mitochondrial membrane and competitively inhibits ADP and ATP transport. The toxicity of ATR in medical herbs can be reduced by hydrothermal processing, but the mechanisms of ATR degradation are not well understood. In this study, GC-MS coupled with SPE and TMS derivatisation was used to detect ATR levels in traditional Chinese medicinal herbs. Our results suggest that ATR molecules were disrupted by decomposition, hydrolysis and saponification after heating with water (decoction) for a long period of time. Hydrothermal processing could decompose the endogenous toxic compounds and also facilitate the detoxification of raw materials used in the Chinese medicine industry.
Clinical observation on treatment of dysthymia with combined use of Xiaochaihu Decoction and doxepin
ZHANG Xue-Zhen
Zhong Xi Yi Jie He Xue Bao , 2005,
Abstract:
保和汤加味治疗冠心病心绞痛52例
张蕾蕾,金华,金钊
中国中医药信息杂志 , 2005,
Abstract: 目的 观察保和汤加味治疗冠心病心绞痛的临床疗效。方法 采用单盲对照法分为2组,均予基础治疗(西药),治疗组(52例)患者在基础治疗的同时使用保和汤加味内服,对照组(46例)患者在基础治疗的同时使用复方丹参片内服,用药2～4个疗程后进行随诊评定。结果 2组总体疗效比较,治疗组明显优于对照组(P<0.05)；对临床主要症状、心电图缺血性ST-T改变均有明显改善作用,且患者消心痛用量亦有明显减少,与对照组比较差异显著(P<0.05)；对尿酸(UA)、高敏C-反应蛋白(HS-CRP)亦有明显降低作用,与对照组比较差异显著(P<0.05,P<0.01)。结论 保和汤加味治疗冠心病心绞痛有良好效果
柴葛解肌汤配方颗粒与传统煎剂中黄芩苷含量的比较研究
徐以亮
中国中医药信息杂志 , 2006,
Abstract: 目的 建立柴葛解肌汤中黄芩苷含量的HPLC测定方法。方法 色谱柱：Kromasil C18(200 mm×4.6 mm,5 ?m)；流动相：甲醇-水-磷酸(47∶53∶0.2)；检测波长：280 nm；柱温：室温；流速：1.0 mL/min。结果 在0.3373～1.6865 ?g范围内峰面积与黄芩苷含量呈线性关系(r=0.9997),平均回收率为97.87%,RSD=1.66%。结论 利用HPLC法测定柴葛解肌汤中黄芩苷含量操作简单,结果准确
调脂护肝方治疗脂肪肝临床研究
吴圣良,张美稀,王怀村,王昌信
中国中医药信息杂志 , 2005,
Abstract: 目的 探讨调脂护肝方治疗脂肪肝的疗效。方法 共观察病例100例,随机分为治疗组(60例)和对照组(40例)。治疗组给予调脂护肝方,每日1剂；对照组口服东宝肝泰片。两组均连续服药3个月。结果 调脂护肝方在改善症状、血脂、肝功能、肝纤维化指标方面与对照组比较有显著差异。结论 调脂护肝方治疗脂肪肝疗效确切
Clinical Practice Examples of Dachaihu Decoction  [PDF]
Hongmei Zhu
Chinese Medicine (CM) , 2013, DOI: 10.4236/cm.2013.42007
Abstract:

This paper mainly describes the experiences of clinical application of Dachaihu Decoction in treating chronic pelvic infection, coronary heart disease, insomnia, and hepatolithiasis.

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