This observational cohort study investigated the utility of the Griffiths III developmental assessment tool in evaluating children with ASD in India, with a focus on identifying developmental profiles. ASD is a neurodevelopmental disorder characterised by impairments in social communication, restricted interests, and repetitive behaviours. The Griffiths III, a widely used developmental assessment tool, provides an overall measure of a child’s development across five domains. This study investigated the use of the Griffiths III in assessing children with ASD and examined its potential in identifying developmental profiles. The study examined 100 children aged 1 - 6 years diagnosed with ASD using ADOS-2 and/or DSM-V criteria. Developmental assessments were conducted using the Griffiths III, supplemented by caregiver reports and medical records. The study revealed distinct developmental profiles through domain Scaled Score Profiles. Notable findings included atypical patterns in task attempts and completion compared to typical developmental sequences. The Griffiths III proved valuable in identifying developmental patterns and informing intervention strategies in children with ASD. These findings suggest the tool’s effectiveness in both initial assessment and monitoring developmental progress in children with ASD within the Indian context.
References
[1]
Abdelmoneim, Z., Eltaher, H., Hussein, M. A., & Hashish, M. E. (2025). Neurodevelopmental Assessment of Early Treated Children with Phenylketonuria: Insights from Griffith III Scales. European Journal of Pediatrics, 184, Article No. 554. https://doi.org/10.1007/s00431-025-06384-2
[2]
Akshoomoff, N. (2006). Use of the Mullen Scales of Early Learning for the Assessment of Young Children with Autism Spectrum Disorders. Child Neuropsychology, 12, 269-277. https://doi.org/10.1080/09297040500473714
[3]
Aylward, G. P. (2009). Developmental Screening and Assessment: What Are We Thinking? Journal of Developmental & Behavioral Pediatrics, 30, 169-173. https://doi.org/10.1097/dbp.0b013e31819f1c3e
[4]
Cirnigliaro, L., Valle, M. S., Casabona, A., Randazzo, M., La Bruna, F., Pettinato, F. et al. (2025). The Developmental Autism Early Screening (DAES): A Novel Test for Screening Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 55, 221-236. https://doi.org/10.1007/s10803-023-06184-3
[5]
Colombi, C., Chericoni, N., Bargagna, S., Costanzo, V., Devescovi, R., Lecciso, F. et al. (2023). Case Report: Preemptive Intervention for an Infant with Early Signs of Autism Spectrum Disorder during the First Year of Life. Frontiers in Psychiatry, 14, Article 1105253. https://doi.org/10.3389/fpsyt.2023.1105253
[6]
Elbaum, B., & Celimli-Aksoy, S. (2017). Empirically Identified Subgroups of Children Served in Part C Early Intervention Programs. Journal of Developmental & Behavioral Pediatrics, 38, 510-520. https://doi.org/10.1097/dbp.0000000000000475
[7]
Filipek, P. A., Accardo, P. J., Ashwal, S., Baranek, G. T., Cook, E. H., Dawson, G. et al. (2000). Practice Parameter: Screening and Diagnosis of Autism: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Child Neurology Society. Neurology, 55, 468-479. https://doi.org/10.1212/WNL.55.4.468
[8]
Jansen, J. M., Green, E., Stroud, L. A., & Watson, M. B. (2020). Using the Griffiths III and Quartile Charts in Assessing Autism Spectrum Disorder: A Case Study. Journal of Education and Learning, 9, 30-40. https://doi.org/10.5539/jel.v9n1p30
[9]
Landa, R., & Garrett‐Mayer, E. (2006). Development in Infants with Autism Spectrum Disorders: A Prospective Study. Journal of Child Psychology and Psychiatry, 47, 629-638. https://doi.org/10.1111/j.1469-7610.2006.01531.x
[10]
Lecciso, F., Martis, C., & Levante, A. (2025). The Use of Griffiths III in the Appraisal of the Developmental Profile in Autism: A Systematic Search and Review. Brain Sciences, 15, Article 506. https://doi.org/10.3390/brainsci15050506
[11]
Li, P. Y., Fu, N. N., Li, Q. Y., Wang, G. F., Gao, L., & Zhang, X. (2020). The Griffiths Development Scales-Chinese (GDS-C): A Reliable and Valid Neurodevelopmental Assessment Tool in Children with ASD Aged 3-8 Years Old in Tianjin, China. Asian Journal of Psychiatry, 52, Article 102144. https://doi.org/10.1016/j.ajp.2020.102144
[12]
Lord, C., & Bishop, S. L. (2015). Recent Advances in Autism Research as Reflected in DSM-5 Criteria for Autism Spectrum Disorder. Annual Review of Clinical Psychology, 11, 53-70. https://doi.org/10.1146/annurev-clinpsy-032814-112745
[13]
Luyster, R., Gotham, K., Guthrie, W., Coffing, M., Petrak, R., Pierce, K. et al. (2009). The Autism Diagnostic Observation Schedule—Toddler Module: A New Module of a Standardized Diagnostic Measure for Autism Spectrum Disorders. Journal of Autism and Developmental Disorders, 39, 1305-1320. https://doi.org/10.1007/s10803-009-0746-z
[14]
Martelli, M. E., Gigliotti, F., Giovannone, F., Lentini, G., Manti, F., & Sogos, C. (2025). Developmental Patterns in Autism and Other Neurodevelopmental Disorders in Preschool Children. Children, 12, Article 125. https://doi.org/10.3390/children12020125
[15]
Mullen, E. M. (1995). Mullen Scales of Early Learning. AGS Edition. American Guidance Service.
Pen?a, E. D., Spaulding, T. J., & Plante, E. (2006). The Composition of Normative Groups and Diagnostic Decision Making: Shooting Ourselves in the Foot. American Journal of Speech-Language Pathology, 15, 247-254. https://doi.org/10.1044/1058-0360(2006/023)
[18]
Shulman, C., Rice, C. E., Morrier, M. J., & Esler, A. (2020). The Role of Diagnostic Instruments in Dual and Differential Diagnosis in Autism Spectrum Disorder across the Lifespan. Child and Adolescent Psychiatric Clinics of North America, 29, 275-299. https://doi.org/10.1016/j.chc.2020.01.002
[19]
Swineford, L. B., Guthrie, W., & Thurm, A. (2015). Convergent and Divergent Validity of the Mullen Scales of Early Learning in Young Children with and without Autism Spectrum Disorder. Psychological Assessment, 27, 1364-1378. https://doi.org/10.1037/pas0000116
[20]
Taddei, M., Bulgheroni, S., Toffalini, E., Pantaleoni, C., & Lanfranchi, S. (2023). Developmental Profiles of Young Children with Autism Spectrum Disorder and Global Developmental Delay: A Study with the Griffiths III Scales. Autism Research, 16, 1344-1359. https://doi.org/10.1002/aur.2953
[21]
Torras‐Ma?á, M., Gómez‐Morales, A., González‐Gimeno, I., Fornieles‐Deu, A., & Brun‐Gasca, C. (2016). Assessment of Cognition and Language in the Early Diagnosis of Autism Spectrum Disorder: Usefulness of the Bayley Scales of Infant and Toddler Development, Third Edition. Journal of Intellectual Disability Research, 60, 502-511. https://doi.org/10.1111/jir.12291
[22]
Troxel, M., Sheldrick, R. C., Eisenhower, A., & Carter, A. S. (2024). Patterns and Correlates of Developmental Profiles Using the Battelle Developmental Inventory among Children in Early Intervention. Journal of Early Intervention, 46, 544-561. https://doi.org/10.1177/10538151231191757
[23]
Tuiskula, A., Stjerna, S., Saure, E., Mets?ranta, M., & Haataja, L. (2025). Perinatal Asphyxia with No or Mild Hypoxic-Ischaemic Encephalopathy: Two-Year Neurodevelopmental Outcome. Early Human Development, 205, Article 106266. https://doi.org/10.1016/j.earlhumdev.2025.106266
[24]
Werner, E., Dawson, G., Munson, J., & Osterling, J. (2005). Variation in Early Developmental Course in Autism and Its Relation with Behavioral Outcome at 3-4 Years of Age. Journal of Autism and Developmental Disorders, 35, 337-350. https://doi.org/10.1007/s10803-005-3301-6