Diagnostic Performance of Optical Coherence Tomography Angiography Compared with Fundus Fluorescein Angiography in Chronic Central Serous Chorioretinopathy
Background: The detection of a clear vascular network by OCTA was more accurate than by FFA. In our study, the detection of a clear vascular network by OCTA was superior to that by FFA. Ten eyes showed a thick, interlocking filamentous neovascular membrane that was well characterized. Statistics showed that the difference was substantial (p < 0.001). Additionally, in our study, the distinct dye leakage patterns of the CCSC on FA did not correlate with the CNVM shown on OCTA, supporting the idea that OCTA identifies the choroidal neovascular network by depth (flow in the outer retina) and is independent of dye leakage detected on FA. Aim of the Work: To evaluate and study the role of OCT angiography in eyes with chronic CSCR in CNV and non-CNV groups in comparison with fundus fluorescein angiography. Patients and Methods: This is a comparative cross-sectional study. It was performed in the Department of Ophthalmology, Mother Theresa University Hospital, in the period from September 2024 to January 2025. Clinical data and images were obtained from 20 patients (20 eyes), divided into two groups. Results: The ink-blot pattern was the most common FFA finding, as in other studies, occurring in 8 out of 10 cases (80%) of CSCR without CNV and in 9 out of 10 cases (90%) of CSCR with active CNV. These were mainly recurrent cases and might suggest chronicity. Conclusion: As a non-invasive, quick, and dependable angiographic imaging method, OCTA has advantages over FA. The ability to view the retinal and choroidal vasculature in various layers is another benefit of OCTA. The narrow field of view of OCTA (which has been somewhat addressed in certain commercially available devices), inability to detect leakage, difficulty in detecting blood flow below a particular level, and inconsistent image quality are some of its drawbacks.
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