Introduction: Heart failure (HF) is a major public health problem due to its increasing prevalence and impact on morbidity and mortality. Adherence to treatment during heart failure is an essential determinant of treatment effectiveness, but it often remains insufficient. The objective of this study was to evaluate the therapeutic adherence of patients with heart failure and to identify factors associated with the cardiology department of the National Ignace Deen CHU of Conakry. Material and Methods: We conducted a cross-sectional study involving 135 patients hospitalized for IC in the cardiology department of the Ignace Deen National Hospital from September 1, 2024, to June 30, 2025. The study population consisted of patients treated and followed for heart failure for at least 3 months. The variables studied were based on sociodemographic data, possession of health insurance and level of adherence. Treatment adherence was measured using the Girerd scale. Results: Out of 528 patients hospitalized in the department during the study period, 135 patients had heart failure, representing a hospital prevalence of 25.5%. The average age of our patients was 57.6 17 years with a male predominance (59.3%). The majority of patients resided in urban areas (80%). More than half of the patients (66.7%) had no health insurance and 92 (68.14%) had a low socioeconomic level. According to our study, 51.1% of patients had a problem with adherence and the main reason for this non-compliance was medication failure (55.5%) and having a lot of medications to take (78.5%). The main factors associated with poor adherence were lack of social coverage (p = 0.02) and gender (p = 0.02). Conclusion: Heart failure remains a major public health problem. Adherence appears to be a central element in improving patient prognosis.
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