Background and Objective: The persistence or worsening of symptoms of Chronic Rhinosinusitis (CRS) leads to an altered quality of life (QoL) with a negative socio-economic impact. The present study aimed to evaluate the control of CRS symptoms and to identify factors contributing to poor control of the disease in our setting. Methods: An analytical cross-sectional study was conducted in the three Otorhinolaryngology services of the Kinshasa hospitals. CRS patients followed up in these clinics for more than 6 months were re-evaluated in our study. Disease control was assessed according to the European Position Paper on Rhinosinusitis and Nasal Polyps 2020 (EPOS20) guidelines. Results: Out of 137 CRS patients recruited, 22 patients (16.1%) were defined as controlled, 35 patients (25.5%) as partially controlled and 80 patients (58.4%) as uncontrolled. Visual analogue scale (VAS), sinonasal outcome test (SNOT)-22 and Lund-Mackay scores were significantly elevated in patients with uncontrolled CRS (p < 0.001). After multivariate analysis, age < 40 years (ORa = 4.1; p = 0.005), lower level of education (ORa = 3.1; p = 0.017), allergy (ORa = 2.8; p = 0.021), use of indigenous products (ORa = 7.2; p < 0.001) and Lund-Mackay score > 10 (ORa = 3.8; p = 0.007) were identified as factors in poor control of CRS. Conclusion: A large number of patients have uncontrolled CRS in our setting. Management should therefore take into account the factors negatively associated with CRS.
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