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表没食子儿茶素的生物活性研究进展
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Abstract:
绿茶作为一种日益受到关注的健康饮品，其抗癌、抗氧化及抗炎等生物活性被广泛报道。其中，表没食子儿茶素是绿茶中含量较高且生物利用度相对突出的儿茶素类化合物，具有抗肿瘤、抗氧化、抗炎及抗菌等多重药理作用，展现出重要的研究与开发价值。本文系统综述了表没食子儿茶素的多种生物活性及其主要作用机制，总结了表没食子儿茶素的吸收和代谢特征，并对其制剂研究现状进行了梳理与分析。结果表明，表没食子儿茶素在开发为高效、稳定的新型药物分子方面具有良好的应用前景。
Green tea, a health beverage that has garnered increasing attention, is widely reported to possess various biological activities, including anticancer, antioxidant, and anti-inflammatory effects. Among its components, epigallocatechin is a catechin compound found in relatively high concentrations in green tea, with a comparatively prominent bioavailability. It exhibits multiple pharmacological effects such as anti-tumor, antioxidant, anti-inflammatory, and antibacterial properties, demonstrating significant research and development value. This article systematically reviews the diverse biological activities of epigallocatechin and its primary mechanisms of action, summarizes its absorption and metabolic characteristics, and analyzes the current status of its pharmaceutical formulation research. The results indicate that epigallocatechin holds promising application prospects for development into efficient and stable novel pharmaceutical agents.
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