Introduction: HELLP syndrome is a severe complication of preeclampsia, associated with high maternal and fetal morbidity and mortality. This study aims to determine its frequency, prognosis, and risk factors at CHUD-BA. Methods: This was a cross-sectional and descriptive study with a retrospective data collection of medical records of women diagnosed with HELLP syndrome between 2019 and 2023 at CHUD-BA. Data were analyzed using R software. The study received approval from CLERB-UP and the necessary administrative authorizations. Results: The hospital frequency of HELLP syndrome was 0.59% (6 cases per 1000 admissions). The mean age of patients was 27.14 ± 5.33 years. 63.51% were in a common-law union, and 12.16% had a history of hypertension. The mean gestational age was 32.63 ± 3.75 weeks, and 81.67% of patients delivered via cesarean section. Clinically, 93.24% had headaches, and 64.86% had SBP ≥ 160 mmHg. Biologically, 63.51% had hemoglobin between 7 and 10 g/dL, and 55.41% had complete HELLP according to the Tennessee classification. The maternal prognosis was favorable in 94.59%, with a maternal mortality rate of 5.41%. Perinatal mortality was 28.33%. Conclusion: HELLP syndrome remains rare but severe, with significant maternal and fetal mortality. Early detection of associated factors could improve management and reduce complications.
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