Breast Cancer: Epidemiological, Histological, and Therapeutic Aspects in the Department of Obstetrics and Gynecology at the National Hospital Donka, Conakry University Teaching Hospital

Objective: To study the epidemiological, histological, and therapeutic characteristics of breast cancer in the Department of Obstetrics and Gynecology at the National Hospital Donka, Conakry University Teaching Hospital. Methods: This was a retrospective descriptive study involving 72 patients with breast cancer managed between January 1, 2010, and December 31, 2022. Data were collected from medical records and focused on epidemiological, histological, and therapeutic aspects. Results: Breast cancer accounted for 11.9% of the 602 gynecological and breast tumors recorded, ranking second. The mean age of patients was 43.5 ± 3.5 years, and 81.6% were multiparous. A family history of breast cancer was found in 37.5% of patients. The consultation delay exceeded 4 months in 50.8% of cases. A breast mass was the main reason for consultation (49%). Nearly half of the patients (49%) were diagnosed at T3 and T4 stages. Invasive ductal carcinoma was the most frequent histological type (53.6%). Modified radical surgery combined with axillary lymph node dissection and adjuvant chemotherapy was performed in 67.3% of patients. The in-hospital mortality rate was 10.2%, and the observed overall survival at 18 months was 75.5%. Conclusion: Breast cancer is a common gynecological malignancy in our department, affecting relatively young women and being predominantly diagnosed at an advanced stage. Invasive ductal carcinoma predominates, and surgery remains the main treatment modality.