Association between Dengue Fever and Pregnancy at the Sour？ Sanou University Hospital Center in Bobo-Dioulasso, Burkina Faso, Based on 58 Cases: Clinical, Biological, and Prognostic Aspects
Objective: The objective of this study was to describe the clinical, biological, and prognostic aspects of dengue and pregnancy in pregnant women hospitalized in a university hospital in Burkina Faso from August 1, 2023, to February 7, 2024. Methodology: This was a descriptive cohort study conducted from August 1, 2023, to February 7, 2024. It involved 58 pregnant women admitted to the obstetrics department of the Sour？ Sanou University Hospital Center who had a confirmed diagnosis of dengue fever. The variables investigated were the clinical, biological, and prognostic aspects of this association. Data were collected through direct individual interviews supplemented by a literature review and recorded on a written questionnaire. The analysis was performed using Epi-Info software version 7.0.9.7. Results: The frequency of dengue fever and pregnancy was 2.08% of all pregnant women admitted to the emergency department. The average age of the patients was 26.8 years and the average gestational age was 2.6 months. Patients who were in the third trimester of their pregnancy accounted for 38%. The main complications were hemorrhage, hepatic cytolysis, intrauterine fetal death, and prematurity. Perinatal mortality was 13.8% and maternal mortality was 1.7%. Conclusion: Maternal and fetal complications are common in cases of dengue fever and pregnancy. When faced with any fever in a pregnant woman in our context, healthcare providers should systematically consider the diagnosis of dengue until proven otherwise. Infected women should then receive multidisciplinary follow-up until delivery.
References
[1]
Chidiac, C. and Ferry, T. (2016) Emerging Infectious Agents. Transfusion Clinique et Biologique, 23, 253-262. https://doi.org/10.1016/j.tracli.2016.08.007
[2]
Strobel, M. and Lamaury, I. (2001) Dengue Fever: Update. La Revue de Médecine Interne, 22, 638-647. https://doi.org/10.1016/s0248-8663(01)00401-5
[3]
Failloux, A. (2016) The Emergence of Arboviruses: Chikungunya and Zika. Bulletin de l’Académie Nationale de Médecine, 200, 1589-1603. https://doi.org/10.1016/s0001-4079(19)30570-9
[4]
Leblanc, R. (2009) Viral Infections in Late Pregnancy. Option/Bio, 20, 9-14. https://doi.org/10.1016/s0992-5945(09)70088-1
[5]
Simmons, C.P., Farrar, J.J., van Vinh Chau, N. and Wills, B. (2012) Dengue. NewEnglandJournalofMedicine, 366, 1423-1432. https://doi.org/10.1056/nejmra1110265
[6]
Sharma, S., Jain, S. and Rajaram, S. (2016) Spectrum of Maternofetal Outcomes during Dengue Infection in Pregnancy: An Insight. InfectiousDiseasesinObstetricsandGynecology, 2016, Article ID: 5046091. https://doi.org/10.1155/2016/5046091
[7]
Kabore, F. (2016) Dengue and Pregnancy in the Obstetrics Department of the Yalgado Ouédraogo University Hospital: Clinical, Biological and Prognostic Aspects of 12 Cases. Master’s Thesis, University of Ouagadougou, 32-40.
[8]
Lompo, Y., Kiemtore, S. and Thieba/Bonane, B. (2023) Ovarian Prognosis of Dengue fever Occurring during Pregnancy at the Yalgado Ouédraogo University Hospital Centre in Ouagadougou (Burkina Faso). Journal de la Sago, 24, 29-34.
[9]
Lefevre, M.R.A. (2010) Descriptive Analysis of the Management of Dengue Patients in New Caledonia. Master’s Thesis, University of Paris 13-Bobigny ‘Leonard de Vinci’, 115 p.
[10]
Epidemiological Surveillance Service of the Disease Control Directorate (2013) Investigation Report on Suspected Cases of Dengue Fever in the Central Health Region. 130 p.
[11]
Kuo, M., Lu, P., Chang, J., Lin, M., Tsai, J., Chen, Y., et al. (2008) Impact of Renal Failure on the Outcome of Dengue Viral Infection. ClinicalJournaloftheAmericanSocietyofNephrology, 3, 1350-1356. https://doi.org/10.2215/cjn.00020108
[12]
Bouldouyre, M.A. (2005) Predictive Factors for Severity on Admission during a Dengue 1 Epidemic at the CHT in Nouméa (New Caledonia). Ph.D. Thesis, University of Saint Antoine-Paris, 90 p.
[13]
Carles, G., Peiffer, H. and Talarmin, A. (1999) Effects of Dengue Fever during Pregnancy in French Guiana. ClinicalInfectiousDiseases, 28, 637-640. https://doi.org/10.1086/515144
[14]
Basurko, C., Carles, G., Youssef, M. and Guindi, W.E.L. (2009) Maternal and Foetal Consequences of Dengue Fever during Pregnancy. EuropeanJournalofObstetrics&GynecologyandReproductiveBiology, 147, 29-32. https://doi.org/10.1016/j.ejogrb.2009.06.028
[15]
Aubrac, P. and Gauzère, B., (2014) Arboviroses tropicale actualité. Médecine Tropicale de Paris, 20, 5-7.
Nigam, A., Gupta, N. and Saxena, P. (2016) Clinical Profile of Dengue Infection in Pregnancy—A Hospital-Based Study. IndianJournalofMedicalSpecialities, 7, 160-162. https://doi.org/10.1016/j.injms.2016.09.012
[18]
Gentilini, M. (1993) Arbovirus and Related Viral Diseases in Tropical Medicine. Ed. Flammarion, 34 p.
[19]
Sanford, J.P. (1998) Infections à arbovirus. In: Harrison, T.H., Ed., Traité de MédecineInterne, 5ème éd, Flammarion, 244-277.
[20]
Ministry of Health, Directorate General for Health Information and Statistics (2024) Statistical Yearbook 2023. 11-12.
[21]
Agrawal, P., Garg, R., Srivastava, S., Verma, U. and Rani, R. (2014) Obstetrics and Gynaecology Pregnancy Outcome in Women with Dengue Infection in Northern India. Indian Journal of Clinical Practice, 24, Article 1053.
