Sj?gren’s syndrome (SS) is an autoimmune disease that most commonly affects the salivary and lacrimal glands. At present, diagnosis mainly relies on salivary gland biopsy, which is an invasive and relatively complex procedure. In recent years, ultrasonography, as a noninvasive and convenient imaging modality, has been widely applied in the evaluation of salivary gland diseases. By assessing glandular parenchymal characteristics and blood flow distribution, ultrasonography enables evaluation of salivary gland involvement. This article reviews the clinical value of different ultrasonographic techniques in assessing salivary gland lesions in patients with SS from two aspects—parenchymal changes and vascular alterations—and discusses their prospects for clinical application.
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