Tinea capitis is a common superficial fungal infection in China, often leading to inappropriate treatment due to misdiagnosis, which severely impacts patients’ quality of life and mental health. Rapid and accurate diagnosis of tinea capitis has become a core challenge in its treatment. In recent years, significant progress has been made in auxiliary tests for tinea capitis. Wood’s lamp examination and dermatoscopy-guided sampling can significantly improve the positive rate of fungal fluorescence microscopy. Combining fungal culture, histopathology, and molecular diagnostic techniques substantially shortens pathogen identification time. This review summarizes current auxiliary diagnostic methods for tinea capitis and their research advancements, aiming to provide references for establishing stratified, efficient diagnostic strategies in clinical practice. Particular attention is given to how different diagnostic techniques assist in pathogen species identification, thereby providing a basis for individualized treatment.
References
[1]
Chen, X.Q., Zheng, D.Y., Xiao, Y.Y., Dong, B.L., Cao, C.W., Ma, L., et al. (2022) Aetiology of Tinea Capitis in China: A Multicentre Prospective Study. BritishJournalofDermatology, 186, 705-712. https://doi.org/10.1111/bjd.20875
[2]
Dyer, J.M. and Foy, V.M. (2022) Revealing the Unseen: A Review of Wood’s Lamp in Dermatology. The Journal of Clinical and Aesthetic Dermatology, 15, 25-30.
[3]
Lekkas, D., Ioannides, D., Apalla, Z., Lallas, A., Lazaridou, E. and Sotiriou, E. (2018) Dermoscopy for Discriminating between Trichophyton and Microsporum Infections in Tinea Capitis. JournaloftheEuropeanAcademyofDermatologyandVenereology, 32, e234-e235. https://doi.org/10.1111/jdv.14755
[4]
John, A.M., Schwartz, R.A. and Janniger, C.K. (2016) The Kerion: An Angry Tinea Capitis. InternationalJournalofDermatology, 57, 3-9. https://doi.org/10.1111/ijd.13423
[5]
Huang, Z., Chen, M., Peng, Y. and Zhang, R. (2024) Unravelling Childhood Tinea Capitis: A Multi-Dimensional Investigation Using Dermoscopy, Scanning Electron Microscopy and Mass Spectrometry. InfectionandDrugResistance, 17, 727-732. https://doi.org/10.2147/idr.s451200
[6]
Johansen, C.D., Shen, J.J.R., Astvad, K.M.T., Jemec, G.B.E., Christensen, J.J. and Saunte, D.M.L. (2024) Exploring Treatment and Antifungal Resistance in an Outbreak of Tinea Caused by Microsporumaudouinii. Mycoses, 67, e13760. https://doi.org/10.1111/myc.13760
[7]
Zeng, J., Wang, S., Guo, L., Lv, S., Shan, B., Liu, Z., et al. (2023) Pediatric Tinea Capitis in Jilin Province: Analyzing Previous Results from a New Perspective. Mycopathologia, 188, 515-522. https://doi.org/10.1007/s11046-023-00718-0
[8]
Felix, I.T.J., Martins, B.A., dos Santos, C.T.B., Tristão, R.J., Rodrigues, A.R.A., de Ataíde, M.S., et al. (2023) The Role of Trypan Blue as a Conventional and Fluorescent Dye for the Diagnosis of Superficial Mycoses by Potassium Hydroxide (KOH) Testing. Mycopathologia, 188, 815-819. https://doi.org/10.1007/s11046-023-00771-9
[9]
Petrucelli, M.F., Abreu, M.H.D., Cantelli, B.A.M., Segura, G.G., Nishimura, F.G., Bitencourt, T.A., et al. (2020) Epidemiology and Diagnostic Perspectives of Dermatophytoses. Journal of Fungi, 6, Article 310. https://doi.org/10.3390/jof6040310
[10]
Prasad, S., Katta, M.R., Abhishek, S., Sridhar, R., Valisekka, S.S., Hameed, M., et al. (2023) Recent Advances in Lewy Body Dementia: A Comprehensive Review. Disease-a-Month, 69, Article ID: 101441. https://doi.org/10.1016/j.disamonth.2022.101441
[11]
Mayser, P., Nenoff, P., Reinel, D., Abeck, D., Brasch, J., Daeschlein, G., et al. (2020) S1 Guidelines: Tinea Capitis. JDDG: JournalderDeutschenDermatologischenGesellschaft, 18, 161-179. https://doi.org/10.1111/ddg.14026
[12]
Su, C.L., Wang, C.S., Zhang, C.H., et al. (2024) Trichoscopic Characteristics Analysis of 50 Children with Tinea Capitis. Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine, 23, 305-308.
[13]
Shemer, A., Lyakhovitsky, A., Kaplan, B., Kassem, R., Daniel, R., Caspi, T., et al. (2022) Diagnostic Approach to Tinea Capitis with Kerion: A Retrospective Study. PediatricDermatology, 39, 708-712. https://doi.org/10.1111/pde.15021
[14]
Elmas, Ö.F. and Durdu, M. (2023) Histopathology in the Diagnosis of Tinea Capitis: When to Do, How to Interpret? Mycopathologia, 188, 545-552. https://doi.org/10.1007/s11046-023-00711-7
[15]
Eckert, J.C., Ertas, B., Falk, T.M., Metze, D. and Böer-Auer, A. (2015) Species Identification of Dermatophytes in Paraffin-Embedded Biopsies with a New Polymerase Chain Reaction Assay Targeting the Internal Transcribed Spacer 2 Region and Comparison with Histopathological Features. BritishJournalofDermatology, 174, 869-877. https://doi.org/10.1111/bjd.14281
[16]
Waśkiel-Burnat, A., Rakowska, A., Sikora, M., Ciechanowicz, P., Olszewska, M. and Rudnicka, L. (2020) Trichoscopy of Tinea Capitis: A Systematic Review. DermatologyandTherapy, 10, 43-52. https://doi.org/10.1007/s13555-019-00350-1
[17]
Zhi, H., Xia, X., Shen, H., Lv, W., Zhong, Y., Sang, B., et al. (2023) Trichoscopy for Early Diagnosis and Follow-Up of Pet-Related Neonatal Tinea Capitis. Mycopathologia, 188, 571-575. https://doi.org/10.1007/s11046-023-00709-1
Dhaille, F., Dillies, A., Dessirier, F., Reygagne, P., Diouf, M., Baltazard, T., et al. (2019) A Single Typical Trichoscopic Feature Is Predictive of Tinea Capitis: A Prospective Multicentre Study. BritishJournalofDermatology, 181, 1046-1051. https://doi.org/10.1111/bjd.17866
[20]
Meghwal, L., Mehta, S., Gupta, L.K., Balai, M. and Mittal, A. (2024) Trichoscopic and Clinico-Morphological Evaluation of Tinea Capitis. IndianDermatologyOnlineJournal, 15, 437-442. https://doi.org/10.4103/idoj.idoj_439_23
[21]
Meneses, O.M., Donati, A., Silva, F.O., Mimiça, M.J., Machado, C.J. and Veasey, J. (2023) Trichoscopy Patterns of Tinea Capitis and Their Correlation with Mycological Culture Results. JournaloftheAmericanAcademyofDermatology, 88, 166-167. https://doi.org/10.1016/j.jaad.2021.12.010
[22]
Ardigo, M., Agozzino, M., Franceschini, C. and Lacarrubba, F. (2016) Reflectance Confocal Microscopy Algorithms for Inflammatory and Hair Diseases. DermatologicClinics, 34, 487-496. https://doi.org/10.1016/j.det.2016.05.011
[23]
Begum, J., Mir, N.A., Lingaraju, M.C., Buyamayum, B. and Dev, K. (2020) Recent Advances in the Diagnosis of Dermatophytosis. JournalofBasicMicrobiology, 60, 293-303. https://doi.org/10.1002/jobm.201900675
[24]
Gnat, S., Łagowski, D., Nowakiewicz, A., Dyląg, M., Osińska, M. and Sawicki, M. (2020) Detection and Identification of Dermatophytes Based on Currently Available Methods—A Comparative Study. JournalofAppliedMicrobiology, 130, 278-291. https://doi.org/10.1111/jam.14778