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Uterine Smooth Muscle Tumor of Uncertain Malignant Potential (Stump): Diagnostic Challenges and Management
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Abstract:
Uterine smooth muscle tumors of uncertain malignant potential (STUMP) are rare neoplasms that are challenging to distinguish from leiomyomas and leiomyosarcomas. Imaging alone does not allow reliable differentiation of these tumors, and the diagnosis relies on histopathological examination, while immunohistochemical markers may help to stratify recurrence risk. We report the case of a 50-year-old patient presenting with a vascularized abdominopelvic mass, pedunculated from the uterus, associated with peritoneal effusion. Total hysterectomy confirmed the diagnosis of STUMP with moderate nuclear atypia and a borderline mitotic index. Clinical and radiological follow-up after one year showed no recurrence. Long-term surveillance remains mandatory, and further research is required to standardize management.
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