Chronic neck pain is a common and disabling condition, with Myofascial Pain Syndrome (MPS) of the upper trapezius muscle frequently contributing to symptoms. Standard treatments often provide only transient relief, and many patients remain refractory. Ultrasound-guided hydrodissection and botulinum toxin A (BoNT-A) injection are emerging therapies targeting mechanical and neuromuscular contributors to myofascial pain, respectively. However, their combined use has not previously been reported. We present the case of a 30-year-old female with chronic right-sided neck pain lasting over one year, unresponsive to oral medications, physiotherapy, and corticosteroid injections. Examination revealed localized trapezius tenderness and reduced cervical range of motion, without radiographic pathology. The patient underwent an ultra-sound-guided hydrodissection of the upper trapezius, targeting the interfascial plane between the trapezius and underlying musculature. This was followed by BoNT-A injections into three ultrasound-guided trigger points within the muscle. The patient reported immediate pain reduction (NAS 7/10 to 1/10 post-procedure) and sustained improvement at 6 and 12 weeks (3/10 and 2/10, respectively), with restoration of functional capacity and cessation of analgesic use. This is the first case to support the use of combined ultrasound-guided trapezius hydrodissection and botulinum toxin A injection as a novel, safe, and effective option for patients with chronic myofascial neck pain unresponsive to conventional therapy. The dual-modality approach addresses both mechanical adhesions and neuromuscular hyperactivity and may represent a valuable addition to the interventional pain management toolkit. These results warrant further investigation of this technique in the management of chronic myofascial pain syndrome.
References
[1]
Borg-Stein, J. and Simons, D.G. (2002) Myofascial Pain. ArchivesofPhysicalMedicineandRehabilitation, 83, S40-S47. https://doi.org/10.1053/apmr.2002.32155
[2]
Simons, D.G., Travell, J.G. and Simons, L.S. (1999) Myofascial Pain and Dysfunction: The Trigger Point Manual. Vol 1. Lippincott Williams & Wilkins.
[3]
Fernández-de-las-Peñas, C., Dommerholt, J. and Gerwin, R.D. (2018) Trigger Point Dry Needling: An Evidence and Clinical-Based Approach. Elsevier.
[4]
Aoki, K.R. (2001) Review of a Proposed Mechanism for the Antinociceptive Action of Botulinum Toxin Type A. Neurotoxicology, 22, 491-497.
[5]
Albrecht, P.J., et al. (2023) Ultrasound-Guided Hydrodissection in the Management of Cervical Myofascial Pain: A Prospective Cohort Study. Pain Physician, 26, E155-E164.
[6]
Lee, J.H., et al. (2022) Ultrasound-Guided Botulinum Toxin Injections for Trapezius Myofascial Pain: A Randomized Controlled Trial. Muscle Nerve, 65, 550-558.
[7]
Gofeld, M., Bristow, S.J., Chiu, S., et al. (2021) Advances in Ultrasound-Guided Pain Interventions: Evidence and Future Directions. Regional Anesthesia & Pain Medicine, 46, 466-477.
[8]
Côté, P., Wong, J.J., Sutton, D., et al. (2015) The Global Burden of Neck Pain: Estimates from the Global Burden of Disease 2010 Study. Annals of the Rheumatic Diseases, 74, 1225-1231.
[9]
Wu, C.H., Ho, T.Y., Chen, C.Y., et al. (2021) Ultrasound-Guided Hydrodissection for Treating Cervical Myofascial Pain Syndrome: A Retrospective Observational Study. Pain Medications, 22, 948-956.
[10]
Fejer, R., Kyvik, K.O. and Hartvigsen, J. (2005) The Prevalence of Neck Pain in the World Population: A Systematic Critical Review of the Literature. EuropeanSpineJournal, 15, 834-848. https://doi.org/10.1007/s00586-004-0864-4
[11]
Choi, Y.J., et al. (2024) Efficacy of Ultrasound-Guided Hydrodissection for Cervical and Upper Thoracic Myofascial Pain: A 2024 Systematic Review and Meta-Analysis. Journal of Pain Research, 17, 45-59.
[12]
Martínez-Valdes, E., et al. (2023) Image-Guided Botulinum Toxin Injections for Chronic Trapezius Pain: Effects on Muscle Activity and Pain Perception. The Clinical Journal of Pain, 39, 297-306.