Introduction Sickle cell retinopathy is the retinal manifestation of sickle cell disease which is due to the alteration of the parameters that influence blood flow in the retinal capillaries. These ocular complications are multiple and affect practically all structures of the eye-ball. The aim was to identify the main ophthalmological complications in patients with sickle cell disease. Materials and Methods: This was a prospective descriptive study lasting six (6) months from 25 July to 25 December 2022. The study covered all sickle cell patients who consulted the S.O.S sickle cell center in Nongo and who were referred to the ophthalmology department of the army medical-surgical center during the study period. Results: 107 patients (55 males, 52 females) were selected with a ratio of 1.05. Their age ranged from 2 to 45 years. The vast majority of our patients were referred (96.26%). Non-proliferative sickle cell retinopathy was the most common (56.25%). Conclusion: Ocular manifestations of sickle cell disease, including sickle cell retinopathy, represent serious complications that can impair vision. Early detection and management are essential to prevent these complications and preserve the visual health of sickle cell patients.
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