Lupus hepatitis is a rare manifestation of systemic lupus erythematosus. When present, it manifests as frustrating clinical signs and moderate disturbance of liver function. We describe a case of lupus hepatitis revealed by massive epistaxis secondary to hepatocellular failure in a 35-year-old female patient whose diagnosis of lupus was made secondarily. Management consisted of azathioprine and corticosteroids, with good resolution of clinical and laboratory signs.
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