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- 2019

A Cost Effective (QbD) Approach in the Development and Optimization of Rosiglitazone Maleate Mucoadhesive Extended Release Tablets –In Vitro and Ex Vivo

DOI: 10.15171/apb.2019.032

Eranti Bhargav,Haranath Chinthaginjala,Mallela Vijaya Jyothi,Moinuddin Syed,Mounika Jutur,Mrunalini Poura,Mujahid Shaik Mahammad,Muralidhar Pisay,Sailaja Yadav,Suryaprakash Reddy Chappidi,Venkataranganna Marikunte

Keywords: Quality by design, Design of experiment, Carbopol 934P, Sodium carboxymethyl cellulose

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Abstract:

Purpose: The purpose of the study was to develop and optimize rosiglitazone maleate mucoadhesive extended-release tablets by quality by design (QbD) approach. Based on QTPP (quality target product profile) CQAs (critical quality attributes) were identified

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