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Incidência e aspectos de imagem do linfoma pós-transplante hepático em crian?as

DOI: 10.1590/S0100-39842012000100004

Keywords: lymphoma, hepatic transplantation, pediatrics, imaging diagnosis, postoperative complications.

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Abstract:

objective: to evaluate the incidence and imaging findings of lymphoma after liver transplantation in children. materials and methods: the authors reviewed records and imaging studies of children submitted to liver transplantation in the period between 2000 and 2008 in a single institution. results: among 241 children submitted to liver transplantation, with a mean follow-up period of 41.4 ± 26.4 months, 16 (6.6%) had lymphoma. the mean age of the patients who developed lymphoma at the moment of transplantation was lower than in children who did not develop malignancy (23.9 ± 18.9 versus 38.0 ± 48.9 months; p = 0.02). the time interval between liver transplantation and the diagnosis of lymphoma ranged from 6 to 103 months. clinical and radiological presentation was variable and the abdomen was the most common location of the tumor (n = 13; 81.3%), followed by chest and head and neck (n = 4; 25.0% each). imaging findings included adenopathy, mediastinal, pulmonary and mesenteric masses, bowel wall thickening and hepatic and renal nodules. four children (25.0%) died because of complications of lymphoma. conclusion: lymphomas are relatively uncommon and potentially fatal complications that may occur any time after pediatric liver transplantation, presenting different clinical and imaging findings.

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