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PLOS ONE  2012 

Characterization of the Functional Domain of β2-Microglobulin from the Asian Seabass, Lates calcarifer

DOI: 10.1371/journal.pone.0013159

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Abstract:

β2-Microglobulin (β2M) is the light chain of major histocompatibility class I (MHC I) that binds non-covalently with the α heavy chain. Both proteins attach to the antigen peptide, presenting a complex to the T cell to be destroyed via the immune mechanism.

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