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Avalia??o da fun??o diastólica em crian?as e adolescentes diabéticos tipo 1 - Existem sinais precoces de miocardiopatia diabética?

DOI: 10.1590/S0004-27302012000400002

Keywords: cardiomyopathy, diastole, diabetes mellitus, type 1, child, adolescent.

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Abstract:

objectives: to evaluate diastolic function (df) of children and adolescents with type 1 diabetes mellitus (dm1). subjects and methods: cross-sectional study of 67 otherwise healthy diabetic patients, and a control group (n = 84) in regard to age, sex, body mass index (bmi), dopplere-chocardiography, and ecg for both groups; and disease duration, hba1c, microalbuminuria, and serum lipids for dm 1 patients. results: diastolic alterations [(a and e mitral waves, e/a ratio, isovolumic relaxation time (ivrt) and e wave deceleration time (ewdt)] were found in diabetic patients, with higher prevalence among pubertal girls (13-17 years old). ivrt and ewdt correlated positively with bmi (p = 0.028). chronological age and disease duration were predictive factors for mitral a wave (p = 0.004 and 0.033, respectively). conclusions: df alterations were detected in the group of diabetic patients, with greater prevalence among pubertal girls; disease duration and age influenced parameters of df.

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