Impacto da proteína-C reativa no risco cardiovascular de adolescentes

background: several studies suggest that c-reactive protein (crp) is associated with coronary artery disease in adults. however, this association has not been thoroughly explored in cases of adolescents. objective: to evaluate the association between crp and cardiovascular risk factors in obese adolescents. methods: eighty-four adolescents (12.6 ± 1.3 years) of both genders were divided into the following groups: normal weight (n = 28), overweight (n = 28), and obese (n = 28), according to body mass index (bmi). crp levels (ultrasensitive elisa), the lipid profile, and anti-oxldl antibody levels (elisa) were determined after a 12-hour fast. results: the groups were similar in age (p = 0.13) and gender (p = 0.83). total cholesterol, hdl-c, tc/hdl-c, and ldl-c/hdl-c showed significant differences between normal weight and obese groups. there was no significant variation in anti-oxldl levels. crp values were different among the three groups (p < 0.01). crp levels showed a significant association with bmi (β = 2.533), ac (β = 2.645), wc (β = 2.945), tc (β = 0.006), ldl-c (β = 0.006), and anti-oxldl antibodies (β = 0.383), and a negative association with hdl-c (β = -0.017). conclusion: the results indicate that crp is significantly associated with markers of cardiovascular risk in adolescents.