De la hipótesis de la trombina a la inflamación: ？Es una realidad?

the classical pathophysiologic concept of the acute coronary syndromes is the coronary artery thrombosis as a consequence of rupture or vulnerable atherosclerotic plaques. actually, it is also been considered that systemic inflammatory phenomenon play a central role in the plaque instability associated to the atherothrombotic activity of the tissue factor (tf). the throm-botic phenomenon is controlled by tissue factor, stimulating the way of the protease's active receptors (par) and cause a negative cycle between inflammation and coagulation.