Urticaria crónica autoinmunitaria: tratamiento con omalizumab

we report the case of a child with diagnosis of chronic urticaria/angioedema and its evolution upon omalizumab treatment. case report. our patient is a 12-years-old female who suffered for 14 months severe chronic urticaria/angioedema. she had a poor response to the highest doses of combined therapy with 3 antihistamines, steroids and anti-leukotrienes and great impairment of her quality of life. an autologous serum skin test was positive until 1:100 dilutions, leading to the diagnosis of chronic autoimmune urticaria. due to the lack of response to treatment, therapy with omalizumab was administered. a notable reduction in symptoms toward the third dose was observed. after 12 months of this treatment, the patient is asymptomatic and has a negative autologous serum test. conclusion. omalizumab could be a therapeutic option for patients with autoimmune urticaria unresponsive to other treatments.