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Virus sincicial respiratorio y adenovirus: Un estudio clínico comparativo en pacientes internados y sin factores de riesgo

Keywords: clinical outcome, hospitalization length, oxygen therapy, mechanical respiratory assistance.

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Abstract:

acute respiratory infections are the most frequent respiratory diseases in children. the most frequently etiological agents associated with acute lower tract infections are the respiratory syncytial virus (60%), adenovirus (8%) and parainfluenza virus (3%). adenovirus has the worst evolution, with a mortality rate of up to 10% versus 2% with respiratory syncytial virus infections. objective. to compare the clinical outcome of patients with viral isolations from nasopharyngeal secretions positive for respiratory syncytial virus and adenovirus. population, material and methods. retrospective, analytical and transversal study in which clinical histories from patients admitted to the hospital general de ni?os "dr. pedro de elizalde" between january and december 2003 with viral isolations from nasopharyngeal secretions positive for respiratory syncytial virus and adenovirus and without pathological history were analyzed. nasopharyngeal secretions were evaluated by indirect immunofluorescent assay. variables included in the study were respiratory syncytial virus and adenovirus, length of hospitalization, oxygen requirement in days, requirement of mechanical ventilation, death, age and sex. results. 27.5% of the patients had a positive viral identification for adenovirus, and 72.5% for respiratory syncytial virus. there were no differences for any of the analyzed variables. conclusions. there were no difference between the clinical outcomes of patients with viral identifications from nasopharyngeal secretions positive for respiratory syncytial virus and adenovirus.

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