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The chemistry of ferrous bis-glycinate chelateKeywords: chelation, criteria for chelation, ferrochel, amino acid chelates.. Abstract: in order to produce a ferrous chelate tour criteria 1 must be met: 1) the ligand must contain two functional groups which are capable of entering into covalent and coordinate covalent bonds; 2) a ring structure with the ferrous ion being the closing member of the ring must be created; 3) the chelate must be ( sterically possible; and 4) the chelation reaction must be energetically possible. in addition to the above, a totally nutritionally functional ferrous chelate must meet three further criteria: 1) it must have low molecular weight; 2)its stability constant must be nutritionally functional; and 3) the ligand must be metabolizable by the body. when. ferrous iron is reacted with glycine and forms a bis-glycinate chelate, it meets all of the requirements of being both a chelate and being a totally nutritionally functional chelate.
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