Acute human schistosomiasis mansoni

the acute schistosomiasis is the toxemic disease that follow the schistosoma cercariae active penetration trough screen in the immunologicaly naive vertebrate host. the clinical picture starts two to eight weeks after the first contact with the contaminated water. susceptible patients present a syndrome comprising fever, diarrhea, toxemia and hepatosplenomegaly. diagnosis is based on epidemiological and clinical features, presence of schistosoma eggs in the feces, enlargement of abdominal lymph nodes by ultrasonography and by detection of high antibodies levels against the antigen keyhole limpet haemocyanin. different rates of cure have been observed with specific medication and for the most severe clinical presentations the use of steroids reduces the systemic and allergic manifestations.