Influencia de la leptina y la adiponectina sobre el cáncer de próstata

objectives: many studies have investigated the association between obesity, adipose tissue-derived factors (leptin and adiponectin) and prostate cancer (cap) but the results are still inconsistent. methods: the aim of this study was to carry out a comprehensive review of the existing evidence about the role of leptin and adiponectin in prostate carcinogenesis and to provide an overview of it. results: recent evidence suggests that leptin may play a rol in prostate cancer progression, while adiponectin may act as an "anti- prostatic cancer" adipokine. conclusions: obesity may promote the progression of established prostate cancer and and adipokines may provide a molecular mechanism whereby obesity exerts its effects on prostate tumour biology.