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Estudio prospectivo sobre la tasa de detección de cáncer de próstata en nuestro hospital en pacientes del noreste de México con antígeno prostático específico entre 2.6 y 4 ng/ml

DOI: 10.4321/S0004-06142010000400007

Keywords: prostatic cancer, psa, biopsy.

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Abstract:

objectives: to find the detection rate of prostate cancer (pca) in our population with psa values between 2.6 and 4 ng/ml. methods: we included 33 consecutive patients with a median age of 66 years, that had a transrectal ultrasound (trus) guided biopsy with psa between 2.6-4 ng/ml. patients were divided into 2 groups. group 1: patients with normal digital rectal examination (dre) and group 2: patients with dre with asymmetry not definitive of pca. exclusion criteria: known history of pca, intraepithelial neoplasia or positive dre. statistical analysis: chi square, t-student and fischer exact test. results: twenty eight percent of the patients (9) had positive biopsy for pca. fifty six percent (5) were gleason 6 and 44% (4) gleason 7 (3+4). group 1 had 59% (20) and group 2 41% in. in group 1 16% (3) had positive biopsy for pca vs 46% (6) in group 2 (p 0.04) rr 3.07. conclusions: there are traces that the detection rate in our population could be lower in comparison with what has been reported in the literature. dre is crucial in the initial evaluation; asymmetry could increase 3 fold the risk of having pca.

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