Objectives People of low socioeconomic status are shorter than those of high socioeconomic status. The first two years of life being critical for height development, we hypothesized that a low socioeconomic status is associated with a slower linear growth in early childhood. We studied maternal educational level (high, mid-high, mid-low, and low) as a measure of socioeconomic status and its association with repeatedly measured height in children aged 0–2 years, and also examined to what extent known determinants of postnatal growth contribute to this association. Methods This study was based on data from 2972 mothers with a Dutch ethnicity, and their children participating in The Generation R Study, a population-based cohort study in Rotterdam, the Netherlands (participation rate 61%). All children were born between April 2002 and January 2006. Height was measured at 2 months (mid-90% range 1.0–3.9), 6 months (mid-90% range 5.6–11.4), 14 months (mid-90% range 13.7–17.9) and 25 months of age (mid-90% range 23.6–29.6). Results At 2 months, children in the lowest educational subgroup were shorter than those in the highest (difference: ？0.87 cm; 95% CI: ？1.16, ？0.58). Between 1 and 18 months, they grew faster than their counterparts. By 14 months, children in the lowest educational subgroup were taller than those in the highest (difference at 14 months: 0.40 cm; 95% CI: 0.08,0.72). Adjustment for other determinants of postnatal growth did not explain the taller height. On the contrary, the differences became even larger (difference at 14 months: 0.61 cm; 95% CI: 0.26,0.95; and at 25 months: 1.00 cm; 95% CI: 0.57,1.43) Conclusions Compared with children of high socioeconomic status, those of low socioeconomic status show an accelerated linear growth until the18th month of life, leading to an overcompensation of their initial height deficit. The long-term consequences of these findings remain unclear and require further study.
References
[1]
Tanner JM (1992) Growth as a measure of the nutritional and hygienic status of a population. Horm Res 38: Suppl 1106–15.
[2]
Davey Smith G, Hart C, Upton M, Hole D, Gillis C, et al. (2000) Height and risk of death among men and women: aetiological implications of associations with cardiorespiratory disease and cancer mortality. J Epidemiol Community Health 54(2): 97–103.
[3]
Gunnell D, Okasha M, Smith GD, Oliver SE, Sandhu J, et al. (2001) Height, leg length, and cancer risk: a systematic review. Epidemiol Rev 23(2): 313–42.
[4]
Jousilahti P, Tuomilehto J, Vartiainen E, Eriksson J, Puska P (2000) Relation of adult height to cause-specific and total mortality: a prospective follow-up study of 31,199 middle-aged men and women in Finland. Am J Epidemiol 151(11): 1112–20.
[5]
Langenberg C, Shipley MJ, Batty GD, Marmot MG (2005) Adult socioeconomic position and the association between height and coronary heart disease mortality: findings from 33 years of follow-up in the Whitehall Study. Am J Public Health 95(4): 628–32.
[6]
Silventoinen K, Zdravkovic S, Skytthe A, McCarron P, Herskind AM, et al. (2006) Association between height and coronary heart disease mortality: a prospective study of 35,000 twin pairs. Am J Epidemiol 163(7): 615–21.
[7]
Fredriks AM, van Buuren S, Hirasing RA, verloove-Vanhorick SP, Wit JM (2001) Voortgaande toename van de lengtegroei bij Nederlandse kinderen in de periode 1955–1997 (Dutch). Ned Tijdschrift Geneesk 145(27): 1308–15.
[8]
Tanner JM, Davies PS (1985) Clinical longitudinal standards for height and height velocity for North American children. J Pediatr 107(3): 317–29.
[9]
Victora CG, Adair L, Fall C, Hallal PC, Martorell R, et al. (2008) Maternal and child undernutrition: consequences for adult health and human capital. Lancet 371(9609): 340–57.
[10]
Cavelaars AE, Kunst AE, Geurts JJ, Crialesi R, Grotvedt L, et al. (2000) Persistent variations in average height between countries and between socio-economic groups: an overview of 10 European countries. Ann Hum Biol 27(4): 407–21.
[11]
Mortensen LH, Diderichsen F, Arntzen A, Gissler M, Cnattingius S, et al. (2008) Social inequality in fetal growth: a comparative study of Denmark, Finland, Norway and Sweden in the period 1981–2000. J Epidemiol Community Health 62(4): 325–31.
[12]
de Menezes RC, de Lira PI, Leal VS, Oliveira JS, Santana SC, et al. (2012) Determinants of stunting in children under five in Pernambuco, northeastern Brazil. Rev Saude Publica 45(6): 1079–87.
[13]
Drachler Mde L, Bobak M, Rodrigues L, Aertz DR, Leite JC, et al. (2002) The role of socioeconomic circumstances in differences in height of pre-school children within and between the Czech Republic and southern Brazil. Cent Eur J Public Health 10(4): 135–41.
[14]
du Prel X, Kramer U, Behrendt H, Ring J, Oppermann H, et al. (2006) Preschool children's health and its association with parental education and individual living conditions in East and West Germany. BMC Public Health 6: 312.
[15]
Finch BK, Beck AN (2011) Socio-economic status and z-score standardized height-for-age of U.S.-born children (ages 2–6). Econ Hum Biol 9(3): 272–6.
[16]
Howe LD, Tilling K, Galobardes B, Smith GD, Gunnell D, et al. (2012) Socioeconomic differences in childhood growth trajectories: at what age do height inequalities emerge? J Epidemiol Community Health 66(2): 143–8.
[17]
Whincup PH, Cook DG, Shaper AG (1988) Social class and height. Bmj 297(6654): 980–1.
[18]
Herngreen WP, van Buuren S, van Wieringen JC, Reerink JD, Verloove-Vanhorick SP, et al. (1994) Growth in length and weight from birth to 2 years of a representative sample of Netherlands children (born in 1988–89) related to socioeconomic status and other background characteristics. Ann Hum Biol 21(5): 449–63.
[19]
Seguin L, Xu Q, Gauvin L, Zunzunegui MV, Potvin L, et al. (2005) Understanding the dimensions of socioeconomic status that influence toddlers' health: unique impact of lack of money for basic needs in Quebec's birth cohort. J Epidemiol Community Health 59(1): 42–8.
[20]
Jaddoe VW, Bakker R, van Duijn CM, van der Heijden AJ, Lindemans J, et al. (2007) The Generation R Study Biobank: a resource for epidemiological studies in children and their parents. Eur J Epidemiol 22(12): 917–23.
[21]
Jaddoe VW, van Duijn CM, van der Heijden AJ, Mackenbach JP, Moll HA, et al. (2008) The Generation R Study: design and cohort update until the age of 4 years. Eur J Epidemiol 23(12): 801–11.
[22]
Braveman P, Cubbin C, Marchi K, Egerter S, Chavez G (2001) Measuring socioeconomic status/position in studies of racial/ethnic disparities: maternal and infant health. Public Health Rep 116(5): 449–63.
[23]
Dowd JB, Zajacova A, Aiello A (2009) Early origins of health disparities: burden of infection, health, and socioeconomic status in U.S. children. Soc Sci Med 68(4): 699–707.
[24]
Fredriks AM, van Buuren S, Jeurissen SE, Dekker FW, Verloove-Vanhorick SP, et al. (2003) Height, weight, body mass index and pubertal development reference values for children of Turkish origin in the Netherlands. Eur J Pediatr 162(11): 788–93.
[25]
Fredriks AM, van Buuren S, Jeurissen SE, Dekker FW, Verloove-Vanhorick SP, et al. (204) Height, weight, body mass index and pubertal development references for children of Moroccan origin in The Netherlands. Acta Paediatr 93(6): 817–24.
McNamee R (2003) Confounding and confounders. Occup Environ Med 60(3):227–34; quiz 164, 234:
[29]
Kramer MS, Guo T, Platt RW, Vanilovich I, Sevkovskaya Z, et al. (2004) Feeding effects on growth during infancy. J Pediatr 145(5): 600–5.
[30]
Lawson DW, Mace R (2008) Sibling configuration and childhood growth in contemporary British families. Int J Epidemiol 37(6): 1408–21.
[31]
Li L, Manor O, Power C (2004) Early environment and child-to-adult growth trajectories in the 1958 British birth cohort. Am J Clin Nutr 80(1): 185–92.
[32]
Ong KK, Preece MA, Emmett PM, Ahmed ML, Dunger DB (2002) Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: longitudinal birth cohort study and analysis. Pediatr Res 52(6): 863–7.
[33]
Dewey KG, Hawck MG, Brown KH, Lartey A, Cohen RJ, et al. (2005) Infant weight-for-length is positively associated with subsequent linear growth across four different populations. Matern Child Nutr 1(1): 11–20.
[34]
Waterlow JC (1994) Relationship of gain in height to gain in weight. Eur J Clin Nutr 48 Suppl 1:S72–3; discussion S73–4:
[35]
Goldstein H (1995) Multilevel statistical models. 2nd ed. London: Edward Arnold.
[36]
Royston P, Ambler G, Sauerbrei W (1999) The use of fractional polynomials to model continuous risk variables in epidemiology. Int J Epidemiol 28(5): 964–74.
[37]
Rubin DB (1987) Multiple Imputation for Nonresponse in Surveys. New York: NY: John Wiley & Sons.
[38]
Center for Research and Statistics, Rotterdam (COS); http://www.cos.rotterdam.nl; (2005)
[39]
Hokken-Koelega AC, De Ridder MA, Lemmen RJ, Den Hartog H, De Muinck Keizer-Schrama SM, et al. (1995) Children born small for gestational age: do they catch up? Pediatr Res 38(2): 267–71.
[40]
Dubois L, Girard M (2003) Social inequalities in infant feeding during the first year of life. The Longitudinal Study of Child Development in Quebec (LSCDQ 1998–2002). Public Health Nutr 6(8): 773–83.
[41]
Spyrides MH, Struchiner CJ, Barbosa MT, Kac G (2008) Effect of predominant breastfeeding duration on infant growth: a prospective study using nonlinear mixed effect models. J Pediatr (Rio J) 84(3): 237–43.
[42]
Dewey KG (2003) Is breastfeeding protective against child obesity? J Hum Lact 19(1): 9–18.
[43]
Heinig MJ, Nommsen LA, Peerson JM, Lonnerdal B, Dewey KG (1993) Energy and protein intakes of breast-fed and formula-fed infants during the first year of life and their association with growth velocity: the DARLING Study. Am J Clin Nutr 58(2): 152–61.
[44]
Botton J, Heude B, Maccario J, Ducimetiere P, Charles MA (2008) Postnatal weight and height growth velocities at different ages between birth and 5 y and body composition in adolescent boys and girls. Am J Clin Nutr 87(6): 1760–8.
[45]
Fewtrell MS, Doherty C, Cole TJ, Stafford M, Hales CN, et al. (2000) Effects of size at birth, gestational age and early growth in preterm infants on glucose and insulin concentrations at 9–12 years. Diabetologia 43(6): 714–7.
[46]
Forsen T, Eriksson JG, Tuomilehto J, Osmond C, Barker DJ (1999) Growth in utero and during childhood among women who develop coronary heart disease: longitudinal study. Bmj 319(7222): 1403–7.
[47]
Law CM, Shiell AW, Newsome CA, Syddall HE, Shinebourne EA, et al. (2002) Fetal, infant, and childhood growth and adult blood pressure: a longitudinal study from birth to 22 years of age. Circulation 105(9): 1088–92.
[48]
Leunissen RW, Oosterbeek P, Hol LK, Hellingman AA, Stijnen T, et al. (2008) Fat mass accumulation during childhood determines insulin sensitivity in early adulthood. J Clin Endocrinol Metab 93(2): 445–51.
[49]
Parsons TJ, Power C, Manor O (2001) Fetal and early life growth and body mass index from birth to early adulthood in 1958 British cohort: longitudinal study. Bmj 323(7325): 1331–5.
[50]
Singhal A, Cole TJ, Fewtrell M, Deanfield J, Lucas A (2004) Is slower early growth beneficial for long-term cardiovascular health? Circulation 109(9): 1108–13.
[51]
Singhal A, Fewtrell M, Cole TJ, Lucas A (2003) Low nutrient intake and early growth for later insulin resistance in adolescents born preterm. Lancet 361(9363): 1089–97.
[52]
Colhoun HM, Hemingway H, Poulter NR (1998) Socio-economic status and blood pressure: an overview analysis. J Hum Hypertens 12(2): 91–110.
[53]
Laaksonen M, Talala K, Martelin T, Rahkonen O, Roos E, et al. (2008) Health behaviors as explanations for educational level differences in cardiovascular and all-cause mortality: a follow-up of 60 000 men and women over 23 years. Eur J Public Health 18(1): 38–43.
[54]
Langenberg C, Hardy R, Kuh D, Brunner E, Wadsworth M (2003) Central and total obesity in middle aged men and women in relation to lifetime socioeconomic status: evidence from a national birth cohort. J Epidemiol Community Health 57(10): 816–22.
[55]
Manor O, Eisenbach Z, Friedlander Y, Kark JD (2004) Educational differentials in mortality from cardiovascular disease among men and women: the Israel Longitudinal Mortality Study. Ann Epidemiol 14(7): 453–60.
[56]
van Rossem L, Silva LM, Hokken-Koelega A, Arends LR, Moll HA, et al. (2010) Socioeconomic status is not inversely associated with overweight in preschool children. J Pediatr 157(6):929–935 e1:
[57]
Lynch J, Kaplan GA (2000) Socioeconomic position. Social epidemiology. 1st ed. Oxford: Oxford University Press. pp. 13–35.
[58]
Galobardes B, Shaw M, Lawlor DA, Lynch JW, Davey Smith G (2006) Indicators of socioeconomic position (part 1). J Epidemiol Community Health 60(1): 7–12.
[59]
Spencer N (2005) Maternal education, lone parenthood, material hardship, maternal smoking, and longstanding respiratory problems in childhood: testing a hierarchical conceptual framework. J Epidemiol Community Health 59(10): 842–6.
[60]
Thrane N, Sondergaard C, Schonheyder HC, Sorensen HT (2005) Socioeconomic factors and risk of hospitalization with infectious diseases in 0- to 2-year-old Danish children. Eur J Epidemiol 20(5): 467–74.
[61]
Braveman PA, Cubbin C, Egerter S, Chideya S, Marchi KS, et al. (2005) Socioeconomic status in health research: one size does not fit all. Jama 294(22): 2879–88.
