Multiphysical modelling of fluid transport through osteo-articular media

in this study, a multiphysical description of fluid transport through osteo-articular porous media is presented. adapted from the model of moyne and murad, which is intended to describe clayey materials behaviour, this multiscale modelling allows for the derivation of the macroscopic response of the tissue from microscopical information. first the model is described. at the pore scale, electrohydrodynamics equations governing the electrolyte movement are coupled with local electrostatics (gauss-poisson equation), and ionic transport equations. using a change of variables and an asymptotic expansion method, the macroscopic description is carried out. results of this model are used to show the importance of couplings effects on the mechanotransduction of compact bone remodelling.