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Modula??o da prolifera??o fibroblástica e da resposta inflamatória pela terapia a laser de baixa intensidade no processo de reparo tecidual

DOI: 10.1590/S0365-05962006000200006

Keywords: laser therapy, low-level, rats, wound healing.

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Abstract:

background: several studies have been performed to understand the tissue repair process as well as the possible effects of laser therapy in wound healing. objectives: to study the behavior of skin wounds induced in the dorsal region of wistar rats (rattus norvegicus), which were submitted to the low-intensity laser therapy at 3.8 j/cm2 dosage, 15mw potency, during 15 seconds. material and methods: the animals (n=12) were divided into two groups - control and laser-treated. the latter comprised three applications (immediately after surgery, 48 hours and 7 days after induction of surgical wounds). ten days after surgery samples of the wounds were collected and submitted to histopathological and histomorphometric studies. results: neovascularization, fibroblast proliferation and reduced inflammatory infiltrate in surgical wound submitted to laser therapy were demonstrated. conclusion: taken together, the results suggest that low-intensity laser therapy is an effective method to modulate tissue repair, thus significantly contributing to a faster and more organized healing process.

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