Structurally modified superhydrophobic surfaces have become particularly desirable as stable antibacterial surfaces. Because their self-cleaning and water resistant properties prohibit bacteria growth, structurally modified superhydrophobic surfaces obviate bacterial resistance common with chemical agents, and therefore a robust and stable means to prevent bacteria growth is possible. In this study, we present a rapid fabrication method for creating such superhydrophobic surfaces in consumer hard plastic materials with resulting antibacterial effects. To replace complex fabrication materials and techniques, the initial mold is made with commodity shrink-wrap film and is compatible with large plastic roll-to-roll manufacturing and scale-up techniques. This method involves a purely structural modification free of chemical additives leading to its inherent consistency over time and successive recasting from the same molds. Finally, antibacterial properties are demonstrated in polystyrene (PS), polycarbonate (PC), and polyethylene (PE) by demonstrating the prevention of gram-negative Escherichia coli (E. coli) bacteria growth on our structured plastic surfaces.
References
[1]
Scott RD (2008) The direct medical costs of healthcare-associated infections in US hospitals and the benefits of prevention. Center for Disease Control Available at http://www.cdc.gov/ncidod/dhqp/pdf/Scott？_CostPaper.pdf. Accessed 7/1/2009.
[2]
Gaidelyte A, Vaara M, Bamford DH (2006) Bacteria, Phages and Septicemia. PloS ONE 2: 11.
[3]
Klevens RM, Edwards JR, Richards CL, Horan T, Gaynes R, et al. (2007) Estimating healthcare-associated infections in U.S. hospitals, 2002. Public Health Report 122: 160–166.
[4]
Flores GE, Bates ST, Knights D, Lauber CL, Stomaugh J, et al. (2011) Microbial Biogeography of Public Restroom Surfaces. PLoS ONE 6: 11.
[5]
Getchell-White SI, Donowitz LG, Groschel DHM (1989) The Inanimate Environment of an Intensive Care Unit as a Potential Source of Nosocomial Bacteria: Evidence for Long Survival of Acinetabacter calcoaceticus. Infectious Control and Hopsital Epidemiology 10: 402–407.
[6]
Brookes JS, Annand JW, Hammer A, Dembkowski K, Shulman S (2009) Investigation of Bacterial Pathogens on 70 Frequently Used Environmental Surfaces in a Large Urban U.S. University. Journal of Environmental Health 71: 17–21.
[7]
Srinkanth P, Rajaram E, Sudharsanam S, Lakshumanam A, Mariappan USS, et al. (2010) Mobile phones: emerging threat for infection control. Journal of Infection Prevention 11: 87–90.
[8]
Sondi I, Sondi BS (2004) Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria. J of Colloid and Interface Science 275: 177–182.
[9]
Cho KH, Park JE, Osaka T, Park SG (2005) The study of antimicrobial activity and preservative effects of nanosilver ingredient. Electrochemica Acta 51: 956–960.
[10]
Hou S, Burton EA, Simon KA, Blodgett D, Luk Y, et al. (2007) Inhibition of Escherichia coli Biofilm Formation by Self-Assembled Monolayers of Functional Alkanethiols on Gold. App And Environ Microbio 73: 4300–4307.
[11]
Zheng L, Zhu J (2003) Study on antimicrobial activity of chitosan with different molecular weights. Elsevier 54: 527–530.
[12]
Privett BJ, Youn J, Hong SA, Lee J, Han J, et al. (2011) Antibacterial Fluorinated Silica Colliod Superhydrophobic Surfaces. Langmuir 27: 9597–9601.
[13]
Andersson DI, Hughes D (2010) Antibiotic resistance and its cost: is it possible to reverse resistance? Nat Rev Microbio 8: 260–271.
[14]
Cheng YT, Rodak DE, Wong CA, Hayden CA (2006) Effects of micro-and nano-structures of the self-cleaning behavior of lotus leaves. Nanotechnology 17: 1359–1362.
[15]
Helbig R, Nickerl J, Neinhuis C, Werner C (2011) Smart Skin Patterns Protect Springtails. PLoS ONE 6: 9.
[16]
Watson GS, Cribb BW, Watson JA (2011) Contrasting Micro/Nano Architecture on Termite Wings: Two Divergent Strategies for Optimising Success of Colonisation Flights. PLoS ONE 6: 9.
[17]
Xu QF, Wang JN, Sanderson KD (2010) Organic-Inorganic Composite Nanocoatings with Superhydrophobicity, Good Transparency, and Thermal Stability. ACS Nano 4: 2201–2209.
[18]
Ebril HY, Demirel AL, Avci Y, Mert O (2003) Transformation of a Simple Plastic into a Superhydrophobic Surface. Science 299: 1377–1380.
[19]
Gomez GB, Flendrig LM, Cooper JM (2010) Hysteresis and Reversibility of a Superhydrophobic Photopatternable Silicon Elsatomer. Langmuir 26: 7248–7253.
[20]
？ner D, McCarthy TJ (2000) Ultrahydrophobic Surfaces. Effects of Topography Length Scales on Wettability. Langmuir 16: 3453–3456.
[21]
Jokinen V, Sainiemi L, Franssila S (2008) Complex Droplets on Chemically Modified Silicon Nanograss. Adv Mater 20: 3453–3456.
[22]
Guo SS, Sun MH, Shi J, Liu YJ, Huang WH, et al. (2007) Patterning of Hydrophilic Micro Arrays with Superhydrophobic Surrounding Zones. Elsevier 84: 1673–1676.
[23]
Cortese B, D'Amone S, Manca M, Viola I, Cingolani R, et al. (2007) Superhydrophobicity Due to the Hierarchical Scale Roughness of PDMS Surface. Langmuir 24: 2712–2718.
[24]
Genzer J, Efimenko K (2000) Creating Long-Lived Superhydrophobic Polymer Surfaces Through Mechanically Assembled Monolayers. Science 290: 2130–2132.
[25]
Wu J, Xia J, Lei W, Wang B (2010) Superhydrophobic Surface Based on a Coral-Like Hierarchical Structure of ZnO. PLoS ONE 5: 12.
[26]
Vaquette C, Fawzi-Grancher S, Lavalle P, Frochot C, Viriot ML (2006) In vitro biocompatibility of different polyester membranes. Bio-Med Mat And Eng 16: S131–S136.
[27]
Zeus Industrial Products Inc. (2005) Biocompatibility of Plastics. Technical WhitePaper.
[28]
Xia Y, Whitesides GM (1998) Soft Lithography. Annu Rev Mater Sci 28: 153–184.
[29]
Young T (1805) An Essay on the Cohesion of Fluids. Philos Trans R Soc London 95: 65–87.
[30]
Temenoff JS, Mikos AG (2008) Biomaterials: The Intersection of Biology and Materials Science. Pearson Prentice Hall 249–251 p.
[31]
Wenzel RN (1936) Resistance of Solid Surfaces to Wetting by Water. Ind Eng Chem 28: 988–994.
[32]
Cassie ABD, Baxter S (1944) Wettability of Porous Surfaces. Faraday Soc 40: 546–551.
[33]
Whitney HM, Poetes R, Steiner U, Chittka L, Glover BJ (2011) Determining the Contribution of Epidermal Cell Shape to Petal Wettability Using Isogenic Antirrhinum Lines. PLoS ONE 6: 3.
[34]
Ma M, Hill RM (2006) Superhydrophobic Surfaces. Elsevier 11: 193–202.
[35]
Hallab NJ, Bundy KJ, O'Connor K, Moses RL, Jacobs JJ (2001) Evaluation of Metallic and Polymeric Biomaterial Surface Energy and Surface Roughness Characteristics for Directed Cell Adhesion. Tissue Engineering 7: 55–71.
[36]
Yang H, Deng Y (2008) Preparation and physical properties of superhydrophobic papers. J Colloid Inter Sci 325: 588–593.
[37]
Pringle JH, Fletcher M (1986) Influence of Substratum Hydration and Adsorbed Macromolecules on Bacterial Attachment to Surfaces. App And Environ MicroBio 51: 1321–1325.
[38]
Fu CC, Grimes A, Long M, Ferri CGL, Rich BD, et al. (2009) Tunable Nanowrinkles on Shape Memory Polymer Sheets. Advanced Materials 21: 1–5.
[39]
Goral VN, Hsieh YC, Petzold ON, Faris RA, Yuen PK (2011) Hot embossing of plastic microfluidic devices using poly(dimethylsiloxane) molds. J Micromech Microeng 21: 017002.
[40]
Stalder AF, Melchior T, Müller M, Sage D, Blu T, et al. (2010) Low-Bond Axisymmetric Drop Shape Analysis for Surface Tension and Contact Angle Measurements of Sessile Drops. Colloids and Surfaces A: Physicochemical and Engineering Aspects 364: 72–81.
[41]
Zhu L, Xiu Y, Xu J, Tamirisa PA, Hess DW, et al. (2005) Superhydrophobicity on Two-Tier Rough Surfaces Fabricated by Controlled Growth of Aligned Carbon Nanotube Arrays Coated with Fluorocarbon. Langmuir 21: 11208–11212.
