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Terpenoid constituents from leaves of Guarea kunthianaDOI: 10.1590/S0103-50532004000500025 Keywords: guarea kunthiana, meliaceae, diterpenes, sesquiterpenes, ent-kaur-16-en-2-one. Abstract: from leaves of guarea kunthiana one new kaurene diterpene (ent-kaur-16-en-2-one) was isolated along with eight known diterpenes (ent-kaur-16-ene, ent-3a- and 3b-hydroxykaur-16-ene, kolavelool, kolavenol, kolavenal, ent-13-epi-manoyloxide and (-)-nephthenol), four sesquiterpenes (alismol, alismoxide, spathulenol and 4b,10a-aromadendranediol), polyprenol-12 and a- and d-tocopherols. kolavenal is reported for the first time as a natural product, as well as the occurrence of cembrane- and ent-kaurane-type diterpenes in the meliaceae.
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