An Alternative Route for the Synthesis of (E)-(+)-5(S)-Methylhept-2-en-4-one (Filbertone)

we are reporting an alternative methodology to prepare (+)-filbertone (1), a natural flavor isolated from hazelnut extracts. commercially available (-)-2(s)-methylbutan-1-ol (2) was used as starting material and the synthesis was carried out in four steps with an overall yield of 42%. the optical rotation and the enantiomeric purity of the final compound were determined.