A New Germacrane Sesquiterpene from the Brazilian Endemic Gorgonian Phyllogorgia dilatata Esper

a bioassay-guided re-investigation of natural products from the brazilian endemic octocoral phyllogorgia dilatata esper (gorgonacea, gorgoniidae), collected in rio de janeiro state, has revealed three further compounds from this species: the dinoflagellate pigment peridinin (1), the icthyodeterrent diterpene 11b,12b-epoxypukalide (2), both previously reported from other octocoral species, and the new natural sesquiterpene (e) germacra-1(10),4(15),7(11)-trien-5-ol-8-one (3). spectroscopic analysis and comparison with literature data allowed the structure elucidation of 1-3.