Evaluation of a simple hyphenated system for flow injection solid-phase pre-concentration and capillary electrophoresis

in this work, the development and evaluation of a hyphenated flow injection-capillary electrophoresis system with on-line pre-concentration is described. preliminary tests were performed to investigate the influence of flow rates over the analytical signals. results revealed losses in terms of sensitivity of the fia-ce system when compared to the conventional ce system. to overcome signal decrease and to make the system more efficient, a lower flow rate was set and an anionic resin column was added to the flow manifold in order to pre-concentrate the analyte. the pre-concentration fia-ce system presented a sensitivity improvement of about 660% and there was only a small increase of 8% in total peak dispersion. these results have confirmed the great potential of the proposed system for many analytical tasks especially for low concentration samples.