Spruceanumines A and B, novel plumeran indole alkaloids from Aspidosperma spruceanum(Apocynaceae)

two novel indole alkaloids with plumeran skeleton, spruceanumines a (1) and b (2), and eight known indole alkaloids, aspidospermidine (3), demethoxypalosine (4), aspidocarpine (5), aspidolimine (6), fendlerine (7), aspidolimidine (8), obscurinervidine (9) and obscurinervine (10) were isolated from stem bark and seeds methanolic extracts of aspidosperma spruceanum. compounds structures were elucidated on the basis of spectroscopic data, mainly those obtained by 1h and 13c nmr (1d and 2d) and mass spectrometry.