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Pulmonary tuberculosis: hematology, serum biochemistry and the relation with the disease duration

DOI: 10.1590/S1678-91992008000100006

Keywords: mycobacterium tuberculosis, pulmonary tuberculosis, smoking, hematolological and biochemical parameters, erythrocyte sedimentation rate.

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Abstract:

the aim of the present study was to analyze the relationship between hematological and biochemical parameters and tuberculosis process activity time according to clinical complaint duration. it was a retrospective study analyzing medical records from 80 pulmonary tuberculosis patients at botucatu medical school university hospital (botucatu, s?o paulo state, brazil), who were divided into 2 groups according to clinical complaint duration: group 1 (g1) - up to three months; group 2 (g2) - over three months. parameters included: age, gender, bacilloscopy, erythrocyte sedimentation rate (esr), platelet count, alpha1-globulin, alpha2-globulin, gamma globulin, mucoprotein, alpha1-acid glycoprotein values, and the presence of risk factors such as smoking, alcoholism, drug addiction, sexual promiscuity, contact with tuberculosis carriers, and previous treatment. groups were compared by calculating t and p, and chi-square (x2) and p. comparisons revealed a tendency towards smoking with a higher frequency of smokers in g1 (0.050.05). a correlation was found between esr, platelet count, smoking and less than three months clinical duration.

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